Publication Name	World Journal of Stem Cells
Manuscript ID	57914
Country	China

Category	Endocrinology & Metabolism
Manuscript Type	Minireviews
Article Title	Pancreatic β cell regeneration induced by clinical and preclinical agents
Manuscript Source	Invited Manuscript
All Author List	Kang-Li Wang, Ming Tao, Tian-Jiao Wei and Rui Wei
Funding Agency and Grant Number	Funding Agency Grant Number the National Key Research and Development Program of China 2016YFA0100501 the National Natural Science Foundation of China 81770768 and 81970671 the Natural Science Foundation of Beijing 7192225
Corresponding Author	Rui Wei, MD, PhD, Research Associate, Department of Endocrinology and Metabolism, Peking University Third Hospital, 49 North Garden Road, Haidian District, Beijing 100191, China. weirui@bjmu.edu.cn
Key Words	β cell regeneration; β cell dedifferentiation; Cell proliferation; Pancreatic progenitors; α-to-β cell transdifferentiation; Enteroendocrine progenitor cells
Core Tip	Pancreatic regeneration is a potential therapeutic strategy for β cell recovery in diabetes. Previous studies have focused on the various cell types and different strategies for islet regeneration. However, how far this is from clinical application has not been fully elucidated. In this review, we focus on the clinical and preclinical agents used in different approaches. The clinical potential and disadvantages of the various approaches are discussed, and some suggestions are made for future perspectives.
Citation	Wang KL, Tao M, Wei TJ, Wei R. Pancreatic β cell regeneration induced by clinical and preclinical agents. World J Stem Cells 2021; 13(1): 64-77

Received	2020-06-29 10:26
Peer-Review Started	2020-06-29 10:27
To Make the First Decision
Return for Revision	2020-10-21 20:24
Revised	2020-11-16 08:43
Second Decision	2020-11-26 10:17
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief	2020-11-29 22:20
Articles in Press	2020-11-29 22:20
Publication Fee Transferred
Edit the Manuscript by Language Editor	2020-12-07 08:14
Typeset the Manuscript	2021-01-18 06:19

ISSN	1948-0210 (online)
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