Publication Name	World Journal of Clinical Cases
Manuscript ID	60287
Country	China

Category	Pathology
Manuscript Type	Case Report
Article Title	Novel intergenic KIF5B-MET fusion variant in a patient with gastric cancer: A case report
Manuscript Source	Unsolicited Manuscript
All Author List	Zhi-Wei Wu, Yu Sha, Qing Chen, Juan Hou, Yan Sun, Wang-Kun Lu, Jing Chen and Li-Jiang Yu
Funding Agency and Grant Number
Corresponding Author	Li-Jiang Yu, BMed, Chief Physician, Department of Oncology, The Seventh Affiliated Hospital of Yangzhou University, Jingjiang People's Hospital, No. 28 Zhongzhou Road, Jingjiang 214500, Jiangsu Province, China. yulijiang830@163.com
Key Words	KIF5B; MET; Gastric cancer; Non-small cell lung cancer; Tumor within a tumor; Case report
Core Tip	In this case report, we reported the discovery of a " tumor within a tumor " in the lung tumor tissue of a 64 years old non-smoking male patient. Combined with the medical history and the results of enzyme labeling, the focal area of the postoperative pathology was considered to be gastric cancer. To seek potential therapeutic regimens, an intergenic region between kinesin family member 5b (KIF5B) and MET fusion was identified, which contains a MET kinase domain and a coil curl domain encoded by KIF5B exons 1-25, which may drive the tumorigenesis.
Citation	Wu ZW, Sha Y, Chen Q, Hou J, Sun Y, Lu WK, Chen J, Yu LJ. Novel intergenic KIF5B-MET fusion variant in a patient with gastric cancer: A case report. World J Clin Cases 2021; 9(14): 3350-3355

Received	2020-11-25 11:38
Peer-Review Started	2020-11-25 11:39
To Make the First Decision
Return for Revision	2021-01-07 04:13
Revised	2021-01-20 16:01
Second Decision	2021-03-02 06:08
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief	2021-03-03 17:20
Articles in Press	2021-03-03 17:20
Publication Fee Transferred
Edit the Manuscript by Language Editor	2021-03-27 10:28
Typeset the Manuscript	2021-04-22 11:49

ISSN	2307-8960 (online)
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