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1/13/2021 5:51:15 PM | Browse: 62 | Download: 76
Publication Name World Journal of Gastroenterology
Manuscript ID 60342
Country/Territory China
Category Gastroenterology and Hepatology
Manuscript Type Basic Study
Article Title Xiangbinfang granules enhance gastric antrum motility via intramuscular interstitial cells of Cajal in mice
Manuscript Source Unsolicited Manuscript
All Author List Qi-Cheng Chen, Zhi Jiang, Jun-Hong Zhang, Li-Xing Cao and Zhi-Qiang Chen
Funding Agency and Grant Number
Funding Agency Grant Number
Specific Research Fund for TCM Science and Technology of Guangdong Provincial Hospital of Chinese Medicine YN10101902
National Regional Traditional Chinese Medicine (Specialist) Clinic Construction (2018)205
Corresponding Author Zhi-Qiang Chen, MD, Professor, The Research Team of TCM Applications of Perioperative, The Second Affiliated Hospital of Guangzhou University of Chinese Medicine, Guangdong Provincial Hospital of Traditional Chinese Medicine, No. 111 Dade Road, Guangzhou 510120, Guangdong Province, China. wssq@gzucm.edu.cn
Key Words Interstitial cells of Cajal; Migrating motor complex; W/Wv; Gastric antrum motility; Xiangbinfang granule; Chinese medicine
Core Tip This study shows that intramuscular interstitial cells of Cajal (ICC-IM) play crucial roles in regulating the gastric antral migrating motor complexes (MMC) activity. It may be an important bridge between vagus, the enteric nervous system and motilin to regulate smooth muscle contraction. Through the muscarinic receptor pathway on ICC-IM, the Chinese medicine Xiangbinfang granule depolarizes smooth muscle cells and initiates an action potential, changing the periodic motion of MMC into a phase III-like contractions pattern of gastric antrum in mice.
Citation Chen QC, Jiang Z, Zhang JH, Cao LX, Chen ZQ. Xiangbinfang granules enhance gastric antrum motility via intramuscular interstitial cells of Cajal in mice. World J Gastroenterol 2021; In press
Received
2020-10-27 01:45
Peer-Review Started
2020-10-27 01:46
To Make the First Decision
Return for Revision
2020-12-13 02:19
Revised
2020-12-24 11:12
Second Decision
2021-01-13 13:32
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief
2021-01-13 17:51
Articles in Press
2021-01-13 17:51
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript
ISSN 1007-9327 (print) and 2219-2840 (online)
Open Access This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/
Copyright © The Author(s) 2021. Published by Baishideng Publishing Group Inc. All rights reserved.
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Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Assistant Editor Assistant Editor
Science Editor Xi-Fang Chen (Part-Time Editor)
Reviewer Code 00000918, and 03476131
Editorial Director
Journal Chief Editor
Company Chief Editor Li Ma
Language Editor
Production Editor
Responsible Production Editor
Responsible Science Editor
Proofing Editorial Director Jin-Lei Wang
Proofing Editor-in-Chief Lian-Sheng Ma
Manuscript File 60342_Auto_Edited.docx
Answering Reviewers 60342-Answering reviewers.pdf
Audio Core Tip 60342-Audio core tip.m4a
Biostatistics Review Certificate 60342-Biostatistics statement.pdf
Conflict-of-Interest Disclosure Form 60342-Conflict-of-interest statement.pdf
Copyright License Agreement 60342-Copyright license agreement.pdf
Approved Grant Application Form(s) or Funding Agency Copy of any Approval Document(s) 60342-Grant application form(s).pdf
Institutional Animal Care and Use Committee Approval Form or Document 60342-Institutional animal care and use committee statement.pdf
Institutional Review Board Approval Form or Document 60342-Institutional review board statement.pdf
Non-Native Speakers of English Editing Certificate 60342-Language certificate.pdf
Peer-review Report 60342-Peer-review(s).pdf
Scientific Misconduct Check 60342-Bing-Chen XF-1.png
Scientific Misconduct Check 60342-Bing-Chen XF-2.png
Scientific Misconduct Check 60342-Scientific misconduct check.pdf
Scientific Editor Work List 60342-Scientific editor work list.pdf