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Publication Name World Journal of Gastroenterology
Manuscript ID 60984
Country/Territory China
Category Gastroenterology and Hepatology
Manuscript Type Retrospective Study
Article Title Effect of liver inflammation on accuracy of FibroScan device in assessing liver fibrosis stage in patients with chronic hepatitis B virus infection
Manuscript Source Unsolicited Manuscript
All Author List Ling-Ling Huang, Xue-Ping Yu, Ju-Lan Li, Hui-Ming Lin, Na-Ling Kang, Jia-Ji Jiang, Yue-Yong Zhu, Yu-Rui Liu and Da-Wu Zeng
Funding Agency and Grant Number
Funding Agency Grant Number
Science and Technology Department of Fujian Province, China 2019Y0015
Science and Technology Department of Fujian Province, China 2019J01432
Chinese National 13th Five-Year Plan's Science and Technology Projects 2017ZX10202201
Quanzhou Science and Technology Project of Fujian Province, China 2018Z074
Corresponding Author Da-Wu Zeng, MD, PhD, Associate Chief Physician, Doctor, Department of Hepatology, Hepatology Research Institute, The First Affiliated Hospital, Fujian Medical University, No. 20 Chazhong Road, Taijiang District, Fuzhou 350005, Fujian Province, China. zengdw1980@fjmu.edu.cn
Key Words Liver stiffness measurement; Fibrosis stage; Liver inflammation; Hepatitis B virus; FibroScan; Predictive model
Core Tip Transient elastography (FibroScan) is a recommended non-invasive test for evaluation of liver fibrosis in patients with chronic hepatitis B virus (HBV) infection. In this study, we demonstrated the good performance of FibroScan in predicting liver fibrosis staging. However, we found that the discordance between Fibroscan fibrosis staging and pathological score. Liver inflammation was an independent risk factor affecting the accuracy of FibroScan assessing HBV related liver fibrosis staging. The combination of other related non-invasive factors can predict the risk of FibroScan staging misdiagnosis, and may be helpful for guiding the diagnosis and therapy of chronic HBV infection.
Citation Huang LL, Yu XP, Li JL, Lin HM, Kang NL, Jiang JJ, Zhu YY, Liu YR, Zeng DW. Effect of liver inflammation on accuracy of FibroScan device in assessing liver fibrosis stage in patients with chronic hepatitis B virus infection. World J Gastroenterol 2021; In press
Received
2020-11-26 16:52
Peer-Review Started
2020-11-26 16:52
To Make the First Decision
Return for Revision
2020-12-21 05:54
Revised
2020-12-30 15:45
Second Decision
2021-01-13 14:25
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief
2021-01-13 17:20
Articles in Press
2021-01-13 17:20
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript
ISSN 1007-9327 (print) and 2219-2840 (online)
Open Access This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/
Copyright © The Author(s) 2021. Published by Baishideng Publishing Group Inc. All rights reserved.
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Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Assistant Editor Assistant Editor
Science Editor Jia-Ru Fan
Reviewer Code 03473714
Editorial Director
Journal Chief Editor
Company Chief Editor Li Ma
Language Editor
Production Editor
Responsible Production Editor
Responsible Science Editor
Proofing Editorial Director Jin-Lei Wang
Proofing Editor-in-Chief Lian-Sheng Ma
Manuscript File 60984_Auto_Edited.docx
Answering Reviewers 60984-Answering reviewers.pdf
Audio Core Tip 60984-Audio core tip.m4a
Biostatistics Review Certificate 60984-Biostatistics statement.pdf
Conflict-of-Interest Disclosure Form 60984-Conflict-of-interest statement.pdf
Copyright License Agreement 60984-Copyright license agreement.pdf
Approved Grant Application Form(s) or Funding Agency Copy of any Approval Document(s) 60984-Grant application form(s).pdf
Signed Informed Consent Form(s) or Document(s) 60984-Informed consent statement.pdf
Institutional Review Board Approval Form or Document 60984-Institutional review board statement.pdf
Non-Native Speakers of English Editing Certificate 60984-Language certificate.pdf
Peer-review Report 60984-Peer-review(s).pdf
Scientific Misconduct Check 60984-Bing-Wang JL-1.png
Scientific Misconduct Check 60984-Bing-Fan JR-2.png
Scientific Misconduct Check 60984-Scientific misconduct check.pdf
Scientific Editor Work List 60984-Scientific editor work list.pdf