Publication Name	World Journal of Clinical Cases
Manuscript ID	61085
Country	China

Category	Hematology
Manuscript Type	Case Report
Article Title	Myelodysplastic syndrome transformed into B-lineage acute lymphoblastic leukemia: A case report
Manuscript Source	Unsolicited Manuscript
All Author List	Ye-Jing Zhu, Xiang-Yu Ma, Yun-Liang Hao and Yun Guan
Funding Agency and Grant Number	Funding Agency Grant Number Shandong Medicine and Health Science Technology Development Plan 2017WSA08039 Jining Key Research and Development Program 2018SMNS008 Doctoral Research Startup Foundation of Jining First People’s Hospital 2019003 TCM Technology Development Plan 20190744
Corresponding Author	Yun Guan, PhD, Doctor, Department of Hematology, Jining First People’s Hospital, No. 6 Jiankang Road, Jining 272000, Shandong Province, China. gyuanun1989@163.com
Key Words	Acute lymphoblastic leukemia; B-lineage acute lymphocytic leukemia; Myelodysplastic syndromes; B-cell acute lymphoblastic leukemia; Case report
Core Tip	We present a case of ring-shaped iron granulocyte myelodysplastic syndrome, with the refractory hemocytopenia of multi-lineage hematopoiesis, that transformed into B-cell acute lymphoblastic leukemia. Even though the lymphoid progression in myelodysplastic syndrome had been reported previously, most displayed myeloid-lymphoid hybrid, B cell acute lymphoblastic leukemia is rarely reported, and the specific mechanism is still unclear. We report a rare lymphoid transformation in order to provide information for the study of specific mechanism, and help doctors to provide appropriate treatment to patients.
Citation	Zhu YJ, Ma XY, Hao YL, Guan Y. Myelodysplastic syndrome transformed into B-lineage acute lymphoblastic leukemia: A case report. World J Clin Cases 2021; 9(19): 5191-5196

Received	2020-12-17 10:10
Peer-Review Started	2020-12-13 13:59
To Make the First Decision
Return for Revision	2021-03-27 14:26
Revised	2021-04-06 13:58
Second Decision	2021-05-08 09:13
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief	2021-05-08 09:51
Articles in Press	2021-05-08 09:51
Publication Fee Transferred
Edit the Manuscript by Language Editor	2021-05-17 08:11
Typeset the Manuscript	2021-06-10 00:22

ISSN	2307-8960 (online)
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