Publication Name	World Journal of Hepatology
Manuscript ID	61093
Country	Egypt

Category	Biochemistry & Molecular Biology
Manuscript Type	Basic Study
Article Title	Promotive action of 2-acetylaminofluorene on hepatic precancerous lesions initiated by diethylnitrosamine in rats: Molecular study
Manuscript Source	Invited Manuscript
All Author List	Amany Helmy Hasanin, Eman K Habib, Nesreen El Gayar and Marwa Matboli
Funding Agency and Grant Number
Corresponding Author	Marwa Matboli, MD, Adjunct Professor, Associate Professor, Medical Biochemistry and Molecular Biology Department, Faculty of Medicine, Ain Shams University, Abbassia, P.O. box 11381, Cairo 11381, Egypt. marwasayed472@yahoo.com
Key Words	Acetylaminofluorene; Hepatic precancerous lesion; Diethylnitrosamine; Autophagy; Apoptosis; MicroRNA
Core Tip	2-Acetylaminofluorene epigenetically regulated the expression of long-noncoding RNA RP11-513I15.6/miRNA-1262/miR-1298 (microRNA, miRNA) resulted in decrease in RAB11A, BAX, and p53 mRNA, and the increase in Cyclin E mRNA leading to increased hepatocyte proliferation and decreased apoptosis promoting hepatocellular promoted precancerous lesion in rat models.
Citation	Hasanin AH, Habib EK, El Gayar N, Matboli M. Promotive action of 2-acetylaminofluorene on hepatic precancerous lesions initiated by diethylnitrosamine in rats: Molecular study. World J Hepatol 2021; 13(3): 328-342

Received	2020-11-23 16:24
Peer-Review Started	2020-11-23 16:24
To Make the First Decision
Return for Revision	2020-12-13 05:14
Revised	2020-12-14 18:17
Second Decision	2021-02-03 10:15
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief	2021-03-03 02:47
Articles in Press	2021-03-03 02:47
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript	2021-03-14 05:11

ISSN	1948-5182 (online)
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