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1/12/2021 6:36:59 PM | Browse: 49 | Download: 44
Publication Name World Journal of Gastroenterology
Manuscript ID 61139
Country/Territory China
Category Gastroenterology and Hepatology
Manuscript Type Retrospective Study
Article Title Washed microbiota transplantation reduces proton pump inhibitor dependency in nonerosive reflux disease
Manuscript Source Unsolicited Manuscript
All Author List Ya-Mei Zheng, Xian-Yun Chen, Jie-Yi Cai, Yu Yuan, Wen-Rui Xie, Jia-Ting Xu, Harry Hua-Xiang Xia, Min Zhang, Xing-Xiang He and Li-Hao Wu
Funding Agency and Grant Number
Corresponding Author Li-Hao Wu, MD, Associate Professor, Department of Gastroenterology, The First Affiliated Hospital of Guangdong Pharmaceutical University, Research Center for Engineering Techniques of Microbiota-Targeted Therapies of Guangdong Province, No. 19 Nonglinxia Road, Yuexiu District, Guangzhou 510030, Guangdong Province, China. wulihao888@126.com
Key Words Nonerosive reflux disease; Washed microbiota transplantation; Proton pump inhibitor dependency; Intestinal bacteria; Lipopolysaccharide; Small intestinal bacterial overgrowth
Core Tip In this study, we demonstrate for the first time that washed microbiota transplantation (WMT) is safe and effective for treating patients with nonerosive reflux disease (NERD) and proton pump inhibitor (PPI) dependency compared with PPI treatment. WMT significantly relieved the symptoms of NERD in patients, reduced PPI dependency, prolonged the duration of symptom remission and reduced symptom recurrence.
Citation Zheng YM, Chen XY, Cai JY, Yuan Y, Xie WR, Xu JT, Xia HHX, Zhang M, He XX, Wu LH. Washed microbiota transplantation reduces proton pump inhibitor dependency in nonerosive reflux disease. World J Gastroenterol 2021; In press
2020-11-29 10:43
Peer-Review Started
2020-11-29 10:43
To Make the First Decision
Return for Revision
2020-12-08 02:26
2020-12-20 07:37
Second Decision
2021-01-12 12:06
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief
2021-01-12 18:36
Articles in Press
2021-01-12 18:36
Publication Fee Transferred
Edit the Manuscript by Language Editor
2021-01-24 08:24
Typeset the Manuscript
ISSN 1007-9327 (print) and 2219-2840 (online)
Open Access This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/
Copyright © The Author(s) 2021. Published by Baishideng Publishing Group Inc. All rights reserved.
Permissions For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Assistant Editor Assistant Editor
Science Editor Jia-Ru Fan
Reviewer Code 05040484, and 05040484
Editorial Director
Journal Chief Editor
Company Chief Editor Li Ma
Language Editor Tian-Qi Wang
Production Editor
Responsible Production Editor
Responsible Science Editor
Proofing Editorial Director Jin-Lei Wang
Proofing Editor-in-Chief Lian-Sheng Ma
Manuscript File 61139_Auto_Edited_WangTQ.docx
Answering Reviewers 61139-Answering reviewers.pdf
Audio Core Tip 61139-Audio core tip.m4a
Biostatistics Review Certificate 61139-Biostatistics statement.pdf
Conflict-of-Interest Disclosure Form 61139-Conflict-of-interest statement.pdf
Copyright License Agreement 61139-Copyright license agreement.pdf
Institutional Review Board Approval Form or Document 61139-Institutional review board statement.pdf
Non-Native Speakers of English Editing Certificate 61139-Language certificate.pdf
Peer-review Report 61139-Peer-review(s).pdf
Scientific Misconduct Check 61139-Bing-Ma YJ-1.jpg
Scientific Misconduct Check 61139-Bing-Fan JR-2.png
Scientific Misconduct Check 61139-Scientific misconduct check.pdf
Scientific Editor Work List 61139-Scientific editor work list.pdf