Publication Name	World Journal of Clinical Cases
Manuscript ID	62141
Country	China

Category	Endocrinology & Metabolism
Manuscript Type	Case Report
Article Title	Paget’s disease of bone: Eleven case reports
Manuscript Source	Unsolicited Manuscript
All Author List	Xin-Yu Miao, Xian-Ling Wang, Zhao-Hui Lyu, Jian-Ming Ba, Yu Pei, Jing-Tao Dou, Wei-Jun Gu, Jin Du, Qing-Hua Guo, Kang Chen and Yi-Ming Mu
Funding Agency and Grant Number	Funding Agency Grant Number Special Scientific Research Project of Military Healthcare 19BJZ29 Beijing Haidian District Health Development Research and Cultivation Program HP-2021-03-80303
Corresponding Author	Xian-Ling Wang, MD, PhD, Chief Doctor, Department of Endocrinology, The First Medical Center, Chinese PLA General Hospital, No. 28 Fuxing Road, Beijing 100853, China. wangxianling1972@sohu.com
Key Words	Paget’s disease of bone; Metabolic bone diseases; Chinese; Case report
Core Tip	Paget’s disease of bone (PDB) is a rare metabolic bone disease in China that has high missed diagnosis and misdiagnosis rates. We retrospectively summarized the clinical data of 11 patients with a diagnosis of PDB to provide additional clinical evidence for the disease. We found that PDB presented with a predisposition toward the older male population, and the main clinical symptoms were bone pain, deformity and a high risk of disability. Early identification of PDB can be made through elevated alkaline phosphatase levels and typical presentations on bone X-ray and from bone tissue biopsy. Bisphosphonates are the first choice to improve the symptoms and prognosis.
Citation	Miao XY, Wang XL, Lyu ZH, Ba JM, Pei Y, Dou JT, Gu WJ, Du J, Guo QH, Chen K, Mu YM. Paget’s disease of bone: Eleven case reports. World J Clin Cases 2021; 9(14): 3478-3486

Received	2020-12-30 12:37
Peer-Review Started	2020-12-30 12:39
To Make the First Decision
Return for Revision	2021-01-24 05:40
Revised	2021-02-02 15:40
Second Decision	2021-03-01 12:21
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief	2021-03-03 19:18
Articles in Press	2021-03-03 19:18
Publication Fee Transferred
Edit the Manuscript by Language Editor	2021-03-15 08:39
Typeset the Manuscript	2021-04-12 01:05

ISSN	2307-8960 (online)
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