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Publication Name World Journal of Gastroenterology
Manuscript ID 62149
Country China
Category Gastroenterology & Hepatology
Manuscript Type Minireviews
Article Title RON in hepatobiliary and pancreatic cancers: Pathogenesis and potential therapeutic targets
Manuscript Source Invited Manuscript
All Author List Shao-Long Chen, Guo-Ping Wang, Dan-Rong Shi, Shu-Hao Yao, Ke-Da Chen and Hang-Ping Yao
Funding Agency and Grant Number
Funding Agency Grant Number
National Natural Sciences Foundation of China 81872883
Zhejiang Major Medical Health & Sciences Technology Foundation Projects WKJ-ZJ-13
Corresponding Author Hang-Ping Yao, PhD, Professor, State Key Laboratory for Diagnosis and Treatment of Infectious Disease, National Clinical Research Center for Infectious Diseases, First Affiliated Hospital, Zhejiang University School of Medicine, No. 79 Qingchun Road, Shangcheng District, Hangzhou 310000, Zhejiang Province, China. yaohangping@zju.edu.cn
Key Words RON; Signal transduction; Hepatobiliary; Pancreatic neoplasms; Molecular targeted therapy
Core Tip The role of RON in cancer pathogenesis has received increased research attention. Hepatobiliary and pancreatic (HBP) cancers have poor prognosis, being reported as having higher rates of cancer-related death because of their high rates of recurrence, metastasis, and invasiveness, and their lack of sensitivity to chemotherapy. In this review, we discuss how RON functions in HBP cancers pathogenesis, as well as its potential role as a therapeutic target in HBP cancers.
Citation Chen SL, Wang GP, Shi DR, Yao SH, Chen KD, Yao HP. RON in hepatobiliary and pancreatic cancers: Pathogenesis and potential therapeutic targets. World J Gastroenterol 2021; 27(20): 2507-2520
Received
2020-12-31 05:37
Peer-Review Started
2020-12-31 05:38
To Make the First Decision
Return for Revision
2021-02-23 03:33
Revised
2021-03-04 10:26
Second Decision
2021-04-09 08:25
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief
2021-04-09 18:14
Articles in Press
2021-04-09 18:14
Publication Fee Transferred
Edit the Manuscript by Language Editor
2021-04-20 09:11
Typeset the Manuscript
2021-05-19 00:51
ISSN 1007-9327 (print) and 2219-2840 (online)
Open Access This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/
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