Publication Name	World Journal of Gastroenterology
Manuscript ID	62292
Country	Egypt

Category	Gastroenterology & Hepatology
Manuscript Type	Review
Article Title	Gastrointestinal and hepatic diseases during COVID-19 pandemic: Manifestations, mechanism and management
Manuscript Source	Invited Manuscript
All Author List	Dina Zakaria Mohamed, Mai El-Sayed Ghoneim, Sally El-Sayed Abu-Risha, Ramy Ahmed Abdelsalam and Mohamed Abdelhalem Farag
Funding Agency and Grant Number
Corresponding Author	Dina Zakaria Mohamed, MSc, Assistant Lecturer, Department of Pharmacology and Toxicology, Faculty of Pharmacy, Tanta University, El-Geish St., Tanta, El-Gharbia Governorate, Arab Republic of Egypt, Tanta 31511, Egypt. m_halem1986@yahoo.com
Key Words	COVID-19; Angiotensin-converting enzyme 2; Gastrointestinal; Inflammatory bowel disease; Liver; Management
Core Tip	The coronavirus disease 2019 (COVID-19) pandemic has affected millions worldwide, with high lethality. In addition to typical respiratory symptoms of COVID-19, gastrointestinal symptoms and hepatic harm have been frequently shown during COVID-19. The main purpose of this article is to focus on the manifestations, mechanisms, and management of the gastrointestinal tract and liver that occurred during COVID-19 course. Therefore, physicians must not undervalue the digestive symptoms during COVID-19 infection and rapidly adjust the treatment options for COVID-19 patients during gastrointestinal symptoms and liver enzyme abnormalities.
Citation	Mohamed DZ, Ghoneim MES, Abu-Risha SES, Abdelsalam RA, Farag MA. Gastrointestinal and hepatic diseases during COVID-19 pandemic: Manifestations, mechanism and management. World J Gastroenterol 2021; 27(28): 4504-4535

Received	2021-01-15 17:45
Peer-Review Started	2021-01-15 17:47
To Make the First Decision
Return for Revision	2021-01-31 02:39
Revised	2021-02-12 18:23
Second Decision	2021-06-07 12:31
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief	2021-06-07 13:22
Articles in Press	2021-06-07 13:22
Publication Fee Transferred
Edit the Manuscript by Language Editor	2021-07-12 03:11
Typeset the Manuscript	2021-07-22 03:07

ISSN	1007-9327 (print) and 2219-2840 (online)
Open Access	This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/
Copyright	© The Author(s) 2021. Published by Baishideng Publishing Group Inc. All rights reserved.
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