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Publication Name World Journal of Gastrointestinal Surgery
Manuscript ID 62456
Country China
Category Gastroenterology & Hepatology
Manuscript Type Retrospective Cohort Study
Article Title Could neoadjuvant chemotherapy increase postoperative complication risk on laparoscopic total gastrectomy? A mono-institutional propensity score-matched study in China
Manuscript Source Unsolicited Manuscript
All Author List Hao Cui, Jian-Xin Cui, Yu-Ning Wang, Bo Cao, Huan Deng, Ke-Cheng Zhang, Tian-Yu Xie, Wen-Quan Liang, Yi Liu, Lin Chen and Bo Wei
Funding Agency and Grant Number
Funding Agency Grant Number
National Basic Research Program of China (973 Program) 2019YFB1311505
National Natural Science Foundation of China 81773135
National Natural Science Foundation of China 82073192
Health Cultivating Foundation for Capital Citizens Z171100000417023
Corresponding Author Bo Wei, MD, PhD, Chief Doctor, Professor, Staff Physician, Department of General Surgery, Institute of General Surgery, Chinese PLA General Hospital, No. 28 Fuxing Road, Beijing 100853, China. 18431143691@163.com
Key Words Neoadjuvant chemotherapy; Gastric cancer; Laparoscope; Total gastrectomy; Morbidity
Core Tip Neoadjuvant chemotherapy (NC) and laparoscopic gastrectomy are crucial parts of integrated perioperative treatment for gastric cancer. However, whether NC significantly affects surgical safety or postoperative complications of laparoscopic gastrectomy, especially laparoscopic total gastrectomy (LTG), remains unclear. In our study, we used the propensity-score matching method to compare short-term outcomes between LTG after NC (NC-LTG) and LTG alone. We found that despite a longer operation time and more blood loss in NC-LTG, indicating surgical difficulty, NC-LTG showed acceptable short-term outcomes compared to LTG, illustrating its safety and feasibility.
Citation Cui H, Cui JX, Wang YN, Cao B, Deng H, Zhang KC, Xie TY, Liang WQ, Liu Y, Chen L, Wei B. Could neoadjuvant chemotherapy increase postoperative complication risk on laparoscopic total gastrectomy? A mono-institutional propensity score-matched study in China. World J Gastrointest Surg 2021; 13(5): 429-442
Received
2021-01-10 05:03
Peer-Review Started
2021-01-10 05:05
To Make the First Decision
Return for Revision
2021-02-13 03:39
Revised
2021-02-27 15:10
Second Decision
2021-04-02 12:14
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief
2021-04-05 04:05
Articles in Press
2021-04-05 04:05
Publication Fee Transferred
Edit the Manuscript by Language Editor
2021-04-17 13:59
Typeset the Manuscript
2021-05-17 09:12
ISSN 1948-9366 (online)
Open Access This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/
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