Publication Name	World Journal of Gastroenterology
Manuscript ID	62758
Country	Italy

Category	Oncology
Manuscript Type	Review
Article Title	Molecular alterations in pancreatic tumors
Manuscript Source	Invited Manuscript
All Author List	Michela Visani, Giorgia Acquaviva, Antonio De Leo, Viviana Sanza, Lidia Merlo, Thais Maloberti, Alba A Brandes, Enrico Franceschi, Monica Di Battista, Michele Masetti, Elio Jovine, Sirio Fiorino, Annalisa Pession, Giovanni Tallini and Dario de Biase
Funding Agency and Grant Number
Corresponding Author	Dario de Biase, MSc, PhD, Assistant Professor, Department of Pharmacy and Biotechnology, University of Bologna, viale Ercolani 4/2, Bologna 40138, Italy. dario.debiase@unibo.it
Key Words	Pancreatic tumors; Molecular alterations; Pancreatic ductal adenocarcinomas; Intraductal papillary mucinous neoplasm; Mutations; Molecular markers
Core Tip	To date, in patients with pancreatic cancer there are not targetable molecules for personalized treatment in clinical practice. The introduction of multi-gene analysis approaches, as massive parallel sequencing, has provided a lot of useful information about the molecular characterization of pancreatic tumors. However, a huge amount of data needs to be properly managed to determine the information that is useful and correct. A deeper knowledge of the molecular alterations characterizing pancreatic neoplasms may lead to new potential therapeutic targets for these tumors.
Citation	Visani M, Acquaviva G, De Leo A, Sanza V, Merlo L, Maloberti T, Brandes AA, Franceschi E, Di Battista M, Masetti M, Jovine E, Fiorino S, Pession A, Tallini G, de Biase D. Molecular alterations in pancreatic tumors. World J Gastroenterol 2021; 27(21): 2710-2726

Received	2021-01-17 17:17
Peer-Review Started	2021-01-17 17:18
To Make the First Decision
Return for Revision	2021-02-09 21:23
Revised	2021-02-25 11:09
Second Decision	2021-04-12 08:59
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief	2021-04-14 17:36
Articles in Press	2021-04-14 17:36
Publication Fee Transferred
Edit the Manuscript by Language Editor	2021-05-07 13:38
Typeset the Manuscript	2021-05-19 01:51

ISSN	1007-9327 (print) and 2219-2840 (online)
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