Publication Name	World Journal of Clinical Cases
Manuscript ID	62772
Country	Colombia

Category	Gastroenterology & Hepatology
Manuscript Type	Review
Article Title	Gastrointestinal manifestations of systemic sclerosis: An updated review
Manuscript Source	Invited Manuscript
All Author List	Adan Luquez-Mindiola, Alexis Javier Atuesta and Andres Jose Gómez-Aldana
Funding Agency and Grant Number
Corresponding Author	Andres Jose Gómez-Aldana, MD, Attending Doctor, Department of Endoscopy, Santa Fe Foundation of Bogotá (Fundación Santa Fe de Bogotá), Cra 7 # 117 15, Bogotá 0000, Please Select, Colombia. andresgomezmd@hotmail.com
Key Words	Systemic sclerosis; Gastrointestinal; Diagnosis; Treatment
Core Tip	Systemic sclerosis is an autoimmune disease characterized by vasculopathy, fibrosis of the skin, and internal organ dysfunction. Gastrointestinal involvement is the most common complication of internal organs, impacting up to 90% of patients. This involvement can affect any region of the gastrointestinal tract from the mouth to the anus, with a predominance of alterations being observed in the upper digestive tract. The gastrointestinal involvement primarily involves the esophagus, small intestine and rectum. The severity of gastrointestinal involvement affects quality of life and is a marker of worse prognosis and mortality in these patients. In this review, the current findings regarding gastrointestinal involvement by this entity are described.
Citation	Luquez-Mindiola A, Atuesta AJ, Gómez-Aldana AJ. Gastrointestinal manifestations of systemic sclerosis: An updated review. World J Clin Cases 2021; 9(22): 6201-6217

Received	2021-01-18 01:34
Peer-Review Started	2021-01-18 01:36
To Make the First Decision
Return for Revision	2021-02-12 03:00
Revised	2021-03-30 03:12
Second Decision	2021-06-07 12:59
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief	2021-06-07 13:16
Articles in Press	2021-06-07 13:16
Publication Fee Transferred
Edit the Manuscript by Language Editor	2021-06-16 03:40
Typeset the Manuscript	2021-07-21 14:15

ISSN	2307-8960 (online)
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