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10/14/2021 3:11:34 AM | Browse: 86 | Download: 156
Publication Name World Journal of Gastrointestinal Pathophysiology
Manuscript ID 63022
Country/Territory Indonesia
Category Genetics and Heredity
Manuscript Type Observational Study
Article Title Prediction of hereditary nonpolyposis colorectal cancer using mRNA MSH2 quantitative and the correlation with nonmodifiable factor
Manuscript Source Invited Manuscript
All Author List Tjahjadi Robert Tedjasaputra, Mochammad Hatta, Muh Nasrum Massi, Rosdiana Natzir, Agussalim Bukhari, Rina Masadah, Muh Lutfi Parewangi, Prihantono Prihantono, Rinda Nariswati and Vincent Tedjasaputra
Funding Agency and Grant Number
Corresponding Author Tjahjadi Robert Tedjasaputra, MD, PhD, Consultant Physician-Scientist, Doctor, Senior Lecturer, Department of Internal Medicine, Tarakan General Hospital, Medical Faculty University of Hasanuddin, Jl. Gunung Sahari XI Dalam 70B RT8 RW 3, Jakarta 10720, DKI Jakarta, Indonesia. rtedjasaputra@yahoo.com
Key Words Colorectal cancer; MSH2 gene; Non-modifiable factors; Risk probability
Core Tip The study has determined a definitive cut-off for grouping colorectal cancer (CRC) with its heredity using the MSH2 mRNA gene expression, which amounts to 11059 fc. The gene expressions may differ between blood and tissue sample of the CRC group, yet none between CRC and control group. Nevertheless, subsequent risk factors of family history and staging are found to be significant toward the heredity. The after-mentioned risk factors act as urgent reminder for highly risky people with family history of CRC and/or high CRC staging to have themselves and their immediate family members to undergo routine examinations as well as strict preventions.
Citation Tedjasaputra TR, Hatta M, Massi MN, Natzir R, Bukhari A, Masadah R, Parewangi ML, Prihantono P, Nariswati R, Tedjasaputra V. Prediction of hereditary nonpolyposis colorectal cancer using mRNA MSH2 quantitative and the correlation with nonmodifiable factor. World J Gastrointest Pathophysiol 2021; 12(6): 130-142
Received
2021-01-27 01:19
Peer-Review Started
2021-01-27 01:26
To Make the First Decision
Return for Revision
2021-03-01 17:13
Revised
2021-03-13 10:34
Second Decision
2021-10-13 06:20
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief
2021-10-14 03:11
Articles in Press
2021-10-14 03:11
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript
2021-11-15 02:27
ISSN 2150-5330 (online)
Open Access This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Noncommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/
Copyright © The Author(s) 2021. Published by Baishideng Publishing Group Inc. All rights reserved.
Permissions For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Assistant Editor Assistant Editor
Science Editor Jia-Ru Fan
Reviewer Code 03442364, 02928870, and 03442364
Editorial Director
Journal Chief Editor
Company Chief Editor Lian-Sheng Ma
Language Editor
Production Editor Jia-Hui Li (Quit 2022)
Responsible Production Editor Jia-Hui Li (Quit 2022)
Responsible Science Editor
Proofing Editorial Director Jin-Lei Wang
Proofing Editor-in-Chief Lian-Sheng Ma
Full Article (PDF) WJGP-12-134.pdf
Full Article (Word) WJGP-12-134.docx
Manuscript File 63022_Auto_Edited.docx
Answering Reviewers 63022-Answering reviewers.pdf
Audio Core Tip 63022-Audio core tip.m4a
Biostatistics Review Certificate 63022-Biostatistics statement.pdf
Conflict-of-Interest Disclosure Form 63022-Conflict-of-interest statement.pdf
Copyright License Agreement 63022-Copyright license agreement.pdf
Signed Informed Consent Form(s) or Document(s) 63022-Informed consent statement.pdf
Institutional Review Board Approval Form or Document 63022-Institutional review board statement.pdf
Non-Native Speakers of English Editing Certificate 63022-Language certificate.pdf
Peer-review Report 63022-Peer-review(s).pdf
Scientific Misconduct Check 63022-Bing-Fan JR-2.png
Scientific Editor Work List 63022-Scientific editor work list.pdf