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Publication Name World Journal of Gastroenterology
Manuscript ID 63093
Country/Territory Italy
Category Gastroenterology and Hepatology
Manuscript Type Minireviews
Article Title Rethinking the Barcelona clinic liver cancer guidelines: Intermediate stage and Child-Pugh B patients are suitable for surgery?
Manuscript Source Invited Manuscript
All Author List Fabrizio Romano, Marco Chiarelli, Mattia Garancini, Mauro Scotti, Mauro Zago, Gerardo Cioffi, Matilde De Simone and Ugo Cioffi
Funding Agency and Grant Number
Corresponding Author Ugo Cioffi, MD, PhD, Full Professor, Surgeon, Department of Surgery, University of Milan, Via F Sforza 35, Milano 20122, Italy. ugocioffi5@gmail.com
Key Words Liver surgery; Hepatocellular carcinoma; Barcelona liver clinic cancer; Child B; Intermediate stage
Core Tip According to Barcelona clinic liver cancer recommendations, intermediate stage hepatocellular carcinomas are excluded from surgery. Also Child-Pugh B patients with hepatocellular carcinomas are not usually candidate to liver resection. Nevertheless, several recent studies demonstrate that surgical resection can provide good survival benefit for patients with large and multinodular (diameter > 5 cm, number > 3) hepatocellular carcinomas or Child-Pugh B cirrhosis. In this review we discuss that liver resection may improve the short- and long-term survival of selected patients who have a stage B hepatocellular carcinoma or in the case of underlying Child-Pugh B cirrhosis.
Citation Romano F, Chiarelli M, Garancini M, Scotti M, Zago M, Cioffi G, De Simone M, Cioffi U. Rethinking the Barcelona clinic liver cancer guidelines: Intermediate stage and Child-Pugh B patients are suitable for surgery? World J Gastroenterol 2021; In press
Received
2021-01-24 11:23
Peer-Review Started
2021-01-24 11:27
To Make the First Decision
Return for Revision
2021-02-22 06:35
Revised
2021-02-24 20:50
Second Decision
2021-04-29 07:05
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief
2021-04-29 11:28
Articles in Press
2021-04-29 11:28
Publication Fee Transferred
Edit the Manuscript by Language Editor
2021-05-06 20:56
Typeset the Manuscript
ISSN 1007-9327 (print) and 2219-2840 (online)
Open Access This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/
Copyright © The Author(s) 2021. Published by Baishideng Publishing Group Inc. All rights reserved.
Permissions For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Assistant Editor Assistant Editor
Science Editor Le Zhang
Reviewer Code 05752753
Editorial Director
Journal Chief Editor
Company Chief Editor Jia-Ping Yan
Language Editor Donna Fox
Production Editor
Responsible Production Editor
Responsible Science Editor
Proofing Editorial Director Jin-Lei Wang
Proofing Editor-in-Chief Lian-Sheng Ma
Manuscript File 63093-Review-FilipodiaCL.docx
Answering Reviewers 63093-Answering reviewers.pdf
Audio Core Tip 63093-Audio core tip.m4a
Conflict-of-Interest Disclosure Form 63093-Conflict-of-interest statement.pdf
Copyright License Agreement 63093-Copyright license agreement.pdf
Non-Native Speakers of English Editing Certificate 63093-Language certificate.pdf
Peer-review Report 63093-Peer-review(s).pdf
Scientific Misconduct Check 63093-Bing-Yan JP-1.jpg
Scientific Misconduct Check 63093-Scientific misconduct check.pdf
Scientific Editor Work List 63093-Scientific editor work list.pdf