Publication Name	World Journal of Clinical Cases
Manuscript ID	63099
Country	China

Category	Critical Care Medicine
Manuscript Type	Case Report
Article Title	Malaria-associated secondary hemophagocytic lymphohistiocytosis: A case report
Manuscript Source	Unsolicited Manuscript
All Author List	Xiao Zhou and Mei-Li Duan
Funding Agency and Grant Number
Corresponding Author	Mei-Li Duan, MD, PhD, Chief Doctor, Professor, Department of Critical Care Medicine, Beijing Friendship Hospital, Capital Medical University, No. 95 Yong'an Road, Xicheng District, Beijing 100054, China. dmeili@ccmu.edu.cn
Key Words	Fever; Malaria; Hemophagocytic lymphohistiocytosis; Secondary; Case report
Core Tip	We found an unexpected association between malaria and hemophagocytic lymphohistiocytosis (HLH) in this case. Literature on malaria-associated HLH is sparse. There are no similar cases reported in China. Through this case, we make the diagnosis based on HLH-2004 criteria and adopt new biomarkers to make the diagnosis of HLH. Through multidisciplinary treatment, the patient was discharged in normal physical condition. This case highlights the importance of early diagnosis and timely therapy of the primary disease to secondary HLH.
Citation	Zhou X, Duan ML. Malaria-associated secondary hemophagocytic lymphohistiocytosis: A case report. World J Clin Cases 2021; 9(22): 6403-6409

Received	2021-01-24 13:51
Peer-Review Started	2021-01-24 13:59
To Make the First Decision
Return for Revision	2021-03-08 00:02
Revised	2021-03-12 12:37
Second Decision	2021-05-08 09:13
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief	2021-05-08 09:54
Articles in Press	2021-05-08 09:54
Publication Fee Transferred
Edit the Manuscript by Language Editor	2021-06-25 08:13
Typeset the Manuscript	2021-07-22 01:47

ISSN	2307-8960 (online)
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