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Publication Name World Journal of Diabetes
Manuscript ID 63333
Country/Territory Hungary
Category Endocrinology & Metabolism
Manuscript Type Minireviews
Article Title Role and function of granin proteins in diabetes mellitus
Manuscript Source Invited Manuscript
All Author List Zoltan Herold, Marton Doleschall and Aniko Somogyi
Funding Agency and Grant Number
Funding Agency Grant Number
the New National Excellence Program of the Ministry for Innovation and Technology from the source of the National Research, Development and Innovation Fund UNKP-20-4-I
Corresponding Author Zoltan Herold, MSc, Research Scientist, Division of Oncology, Department of Internal Medicine and Oncology, Semmelweis University, Tomo u. 25-29, Budapest 1083, Hungary. herold.zoltan@med.semmelweis-univ.hu
Key Words Granin; Chromogranin A; Chromogranin B; Diabetes Mellitus; Mice; Inbred non-obese diabetic; Secretogranin III
Core Tip Granin glycoproteins are secretory proteins that are widely produced by neuronal, neuroendocrine, and endocrine cells throughout the human body. Recent data showed that granin proteins chromogranin A and B, and secretogranin II and III play a role in the carbohydrate metabolism and in the pathophysiology of diabetes mellitus. In this review, the current state of knowledge concerning the relationship between granin proteins, diabetes and glucose homeostasis is discussed in detail, including several ongoing studies pursuing promising granin-based drug therapies for the future of diabetes care.
Citation Herold Z, Doleschall M, Somogyi A. Role and function of granin proteins in diabetes mellitus. World J Diabetes 2021; 12(7): 1081-1092
Received
2021-01-27 11:24
Peer-Review Started
2021-01-27 11:32
To Make the First Decision
Return for Revision
2021-02-25 02:12
Revised
2021-03-05 15:53
Second Decision
2021-05-17 09:03
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief
2021-05-17 12:09
Articles in Press
2021-05-17 12:09
Publication Fee Transferred
Edit the Manuscript by Language Editor
2021-06-07 01:43
Typeset the Manuscript
2021-07-07 06:57
ISSN 1948-9358 (online)
Open Access This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/
Copyright © The Author(s) 2021. Published by Baishideng Publishing Group Inc. All rights reserved.
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