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4/29/2021 11:34:12 AM | Browse: 38 | Download: 20
Publication Name World Journal of Diabetes
Manuscript ID 63533
Country/Territory Italy
Category Endocrinology and Metabolism
Manuscript Type Field of Vision
Article Title Long-term metformin therapy and vitamin B12 deficiency: An association to bear in mind
Manuscript Source Invited Manuscript
All Author List Marco Infante, Martina Leoni, Massimiliano Caprio and Andrea Fabbri
Funding Agency and Grant Number
Corresponding Author Marco Infante, MD, N/A, Adjunct Professor, UniCamillus, Saint Camillus International University of Health Sciences, Via di Sant’Alessandro 8, Rome 00131, Italy. marco.infante@unicamillus.org
Key Words Metformin; Vitamin B12 deficiency; Metformin-induced cobalamin deficiency; Diabetes; Type 2 diabetes; Prediabetes; Screening criteria; Neuropathy; Anemia
Core Tip Over the last decades, vitamin B12 deficiency has been increasingly recognized as a possible consequence of long-term metformin therapy, potentially resulting in clinical manifestations such as hematologic abnormalities and peripheral neuropathy. Metformin-induced vitamin B12 deficiency has relevant implications in light of the growing population of individuals on metformin therapy for the treatment of type 2 diabetes, prediabetes, insulin resistance and polycystic ovary syndrome on a global scale. Notwithstanding, no definite guidelines are currently available for vitamin B12 deficiency screening in metformin-treated patients. We therefore propose a list of criteria for a cost-effective vitamin B12 deficiency screening in metformin-treated patients.
Citation Infante M, Leoni M, Caprio M, Fabbri A. Long-term metformin therapy and vitamin B12 deficiency: An association to bear in mind. World J Diabetes 2021; In press
Received
2021-01-29 00:15
Peer-Review Started
2021-01-29 00:18
To Make the First Decision
Return for Revision
2021-03-16 06:35
Revised
2021-03-21 16:50
Second Decision
2021-04-29 09:04
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief
2021-04-29 11:34
Articles in Press
2021-04-29 11:34
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript
ISSN 1948-9358 (online)
Open Access This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/
Copyright © The Author(s) 2021. Published by Baishideng Publishing Group Inc. All rights reserved.
Permissions For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Assistant Editor Assistant Editor
Science Editor Chen-Chen Gao
Reviewer Code 05847867, 05847900, 05847900, and 05847867
Editorial Director
Journal Chief Editor
Company Chief Editor Jia-Ping Yan
Language Editor
Production Editor
Responsible Production Editor
Responsible Science Editor
Proofing Editorial Director Jin-Lei Wang
Proofing Editor-in-Chief Lian-Sheng Ma
Manuscript File 63533_Auto_Edited-JPY.docx
Answering Reviewers 63533-Answering reviewers.pdf
Audio Core Tip 63533-Audio core tip.m4a
Conflict-of-Interest Disclosure Form 63533-Conflict-of-interest statement.pdf
Copyright License Agreement 63533-Copyright license agreement.pdf
Non-Native Speakers of English Editing Certificate 63533-Language certificate.pdf
Peer-review Report 63533-Peer-review(s).pdf
Scientific Misconduct Check 63533-Bing-Liu M-1.png
Scientific Misconduct Check 63533-Scientific misconduct check.pdf
Scientific Editor Work List 63533-Scientific editor work list.pdf