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11/25/2021 2:43:34 AM | Browse: 68 | Download: 139
Publication Name World Journal of Gastrointestinal Surgery
Manuscript ID 63546
Country/Territory China
Category Pathology
Manuscript Type Review
Article Title Role of mesenteric component in Crohn’s disease: A friend or foe?
Manuscript Source Invited Manuscript
All Author List Yi Yin, Zhen-Xing Zhu, Zhun Li, Yu-Sheng Chen and Wei-Ming Zhu
Funding Agency and Grant Number
Corresponding Author Wei-Ming Zhu, MD, PhD, Chief Doctor, Professor, Department of General Surgery, Jinling Hospital, Medical School of Nanjing University, No. 305 East Zhongshan Road, Nanjing 210002, Jiangsu Province, China. drweimingzhu@126.com
Key Words Crohn’s disease; Mesenteric nerves; Angiogenesis; Lymphatic drainage; Mesenteric adipose tissue
Core Tip Crohn’s disease is a complex autoimmune disease with increasing incidence worldwide, especially in Asian countries in recent years. There has been excellent progress in understanding the role of the mesentery in the pathogenesis and disease progress of Crohn’s disease. The crosstalk between components and intestinal inflammation has aroused many researchers’ interests. Herein, we will discuss the basic function and the alteration under inflammatory state of mesenteric nerves, blood vessels, lymphatics, and fat mass. Existing therapeutic strategies associated with mesentery components will also be summarized.
Citation Yin Y, Zhu ZX, Li Z, Chen YS, Zhu WM. Role of mesenteric component in Crohn’s disease: A friend or foe? World J Gastrointest Surg 2021; 13(12): 1536-1549
Received
2021-01-29 03:43
Peer-Review Started
2021-01-29 03:51
To Make the First Decision
Return for Revision
2021-07-29 04:05
Revised
2021-08-01 08:12
Second Decision
2021-11-24 03:38
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief
2021-11-25 02:43
Articles in Press
2021-11-25 02:43
Publication Fee Transferred
Edit the Manuscript by Language Editor
2021-11-09 20:07
Typeset the Manuscript
2021-12-20 01:45
ISSN 1948-9366 (online)
Open Access This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
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