Publication Name	World Journal of Gastroenterology
Manuscript ID	63552
Country	Australia

Category	Gastroenterology & Hepatology
Manuscript Type	Minireviews
Article Title	Impact of modern antiviral therapy of chronic hepatitis B and C on clinical outcomes of liver disease
Manuscript Source	Invited Manuscript
All Author List	Tiffany Khoo, Danielle Lam and John K Olynyk
Funding Agency and Grant Number
Corresponding Author	John K Olynyk, FAASLD, AGAF, FRACP, MBBS, MD, Professor, Department of Gastroenterology and Hepatology, Fiona Stanley Hospital, 11 Robin Warren Drive, Murdoch 6150, Australia. john.olynyk@health.wa.gov.au
Key Words	Hepatitis B; Hepatitis C; Nucleotide analogues; Directly acting antiviral therapy; Clinical outcomes; Liver disease
Core Tip	Hepatitis B and C infection contribute significantly to the global burden of liver disease. With the introduction of modern antiviral therapy, there is now an effective curative treatment for hepatitis C and potent suppressive antiviral therapy for hepatitis B. Antiviral therapy has had a positive impact on liver disease by reducing hospitalisation rates and hence, cost to global health systems. Rates of decompensation, hepatocellular carcinoma and need for transplantation have all been lowered. This review article assesses the literature and summarises the impact of modern antiviral therapy of chronic hepatitis B and C on clinical outcomes from liver disease.
Citation	Khoo T, Lam D, Olynyk JK. Impact of modern antiviral therapy of chronic hepatitis B and C on clinical outcomes of liver disease. World J Gastroenterol 2021; 27(29): 4831-4845

Received	2021-01-29 04:41
Peer-Review Started	2021-01-29 04:47
To Make the First Decision
Return for Revision	2021-05-02 00:23
Revised	2021-05-14 02:30
Second Decision	2021-07-21 03:32
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief	2021-07-21 07:00
Articles in Press	2021-07-21 07:00
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript	2021-07-27 06:59

ISSN	1007-9327 (print) and 2219-2840 (online)
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