Publication Name	World Journal of Hepatology
Manuscript ID	63811
Country	Türkiye

Category	Gastroenterology & Hepatology
Manuscript Type	Minireviews
Article Title	Acute-on-chronic liver failure in children
Manuscript Source	Invited Manuscript
All Author List	Ali Islek and Gokhan Tumgor
Funding Agency and Grant Number
Corresponding Author	Gokhan Tumgor, MD, Professor, Department of Pediatric Gastroenterology, Cukurova University School of Medicine, -, Adana 01330, Türkiye. gtumgor74@yahoo.com
Key Words	Liver failure; Prognosis; Prevalence; Clinics; Histopathology; Scoring systems; Treatment
Core Tip	Acute-on-chronic liver failure (ACLF) remains poorly defined in pediatric patients. ACLF is associated with acute deterioration in patients with chronic liver disease or cirrhosis due to an underlying precipitating event. In the limited number of pediatric studies conducted to date, the underlying chronic diseases and acute precipitating events have been found to vary among geographical regions, while high rates of short-term mortality have also been reported. This review focuses on ACLF in children.
Citation	Islek A, Tumgor G. Acute-on-chronic liver failure in children. World J Hepatol 2021; 13(10): 1289-1298

Received	2021-02-04 06:08
Peer-Review Started	2021-02-04 06:16
To Make the First Decision
Return for Revision	2021-03-08 06:30
Revised	2021-03-16 17:12
Second Decision	2021-09-17 03:30
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief	2021-09-19 09:05
Articles in Press	2021-09-19 09:05
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript	2021-10-20 06:02

ISSN	1948-5182 (online)
Open Access	This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Copyright	© The Author(s) 2021. Published by Baishideng Publishing Group Inc. All rights reserved.
Permissions	For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher	Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website	http://www.wjgnet.com