Publication Name	World Journal of Stem Cells
Manuscript ID	64233
Country	Italy

Category	Cardiac & Cardiovascular Systems
Manuscript Type	Opinion Review
Article Title	Role of induced pluripotent stem cells in diagnostic cardiology
Manuscript Source	Invited Manuscript
All Author List	Steven B Karch, Vittorio Fineschi, Pietro Francia, Matteo Scopetti, Martina Padovano, Federico Manetti, Alessandro Santurro, Paola Frati and Massimo Volpe
Funding Agency and Grant Number
Corresponding Author	Vittorio Fineschi, MD, PhD, Director, Full Professor, Department of Anatomical, Histological, Forensic and Orthopaedic Sciences, Sapienza University of Rome, Viale Regina Elena 336, Rome 00185, Italy. vittorio.fineschi@uniroma1.it
Key Words	Human induced pluripotent stem cells; Diagnostic cardiology; Heart rhythm disorders; Microelectrode array; Stem cell research; Ethical principles
Core Tip	The introduction of induced pluripotent stem cells (iPSCs) has supplanted the need of human stem cells, thus eliminating most ethical controversies. This methodology has advanced to the point where induced human cardiomyocyte cell lines can also be obtained from commercial sources or tissue banks. iPSCs can predict the behavior of cardiomyocytes in vivo, so that new ways are paved in cardiology research to study arrhythmias and heart disease in general, accelerating the development of new, more effective antiarrhythmic drugs, clinical diagnoses, and personalized medical care.
Citation	Karch SB, Fineschi V, Francia P, Scopetti M, Padovano M, Manetti F, Santurro A, Frati P, Volpe M. Role of induced pluripotent stem cells in diagnostic cardiology. World J Stem Cells 2021; 13(5): 331-341

Received	2021-02-12 12:22
Peer-Review Started	2021-02-12 12:23
To Make the First Decision
Return for Revision	2021-03-17 01:17
Revised	2021-03-27 15:31
Second Decision	2021-04-12 06:42
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief	2021-04-14 17:49
Articles in Press	2021-04-14 17:49
Publication Fee Transferred
Edit the Manuscript by Language Editor	2021-05-07 13:38
Typeset the Manuscript	2021-05-20 15:14

ISSN	1948-0210 (online)
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