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5/8/2021 8:53:58 AM | Browse: 165 | Download: 204
Publication Name World Journal of Gastrointestinal Oncology
Manuscript ID 64580
Country/Territory Italy
Category Gastroenterology & Hepatology
Manuscript Type Review
Article Title Familial adenomatous polyposis and changes in the gut microbiota: New insights into colorectal cancer carcinogenesis
Manuscript Source Invited Manuscript
All Author List Antonio Biondi, Francesco Basile and Marco Vacante
Funding Agency and Grant Number
Corresponding Author Marco Vacante, MD, PhD, Academic Fellow, Doctor, Research Fellow, Department of General Surgery and Medical-Surgical Specialties, University of Catania, Via Santa Sofia 78, Catania 95123, Italy. marcovacante@yahoo.it
Key Words Familial adenomatous polyposis; Microbiota; Colorectal cancer; Polyps; Carcinogenesis; Bacteria
Core Tip A number of studies demonstrated that gut microbiota dysbiosis could represent a key factor in colorectal carcinogenesis. The APCMin/+ mouse model has been extensively used to study the underlying mechanisms of colorectal carcinogenesis in familial adenomatous polyposis. Interventions aimed at improving dysbiosis, through administration of probiotics, prebiotics or antibiotics, could decrease colorectal cancer development in APC mutation carriers.
Citation Biondi A, Basile F, Vacante M. Familial adenomatous polyposis and changes in the gut microbiota: New insights into colorectal cancer carcinogenesis. World J Gastrointest Oncol 2021; 13(6): 495-508
Received
2021-02-20 12:48
Peer-Review Started
2021-02-20 12:51
To Make the First Decision
Return for Revision
2021-03-15 04:44
Revised
2021-03-15 21:40
Second Decision
2021-05-08 07:46
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief
2021-05-08 08:53
Articles in Press
2021-05-08 08:53
Publication Fee Transferred
Edit the Manuscript by Language Editor
2021-05-18 21:32
Typeset the Manuscript
2021-06-04 06:30
ISSN 1948-5204 (online)
Open Access This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/
Copyright © The Author(s) 2021. Published by Baishideng Publishing Group Inc. All rights reserved.
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