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Publication Name World Journal of Orthopedics
Manuscript ID 64688
Country Japan
Category Orthopedics
Manuscript Type Minireviews
Article Title Effects of sclerostin antibody on bone healing
Manuscript Source Invited Manuscript
All Author List Atsushi Mihara, Kiminori Yukata, Toshihiro Seki, Ryuta Iwanaga, Norihiro Nishida, Kenzo Fujii, Yuji Nagao and Takashi Sakai
Funding Agency and Grant Number
Corresponding Author Kiminori Yukata, MD, PhD, Associate Professor, Department of Orthopedic Surgery, Yamaguchi University Graduate School of Medicine, 1-1-1 Minami-Kogushi, Ube 755-8505, Japan. kyukata2004jp@yahoo.co.jp
Key Words Canonical Wnt-β-catenin pathway; Fracture healing; Osteoporosis; Romosozumab; Sclerostin antibody
Core Tip Sclerostin antibody (Scl-Ab) has been recently introduced for the treatment of osteoporosis. Several researchers have reported on the effects of Scl-Ab in bone fracture healing because of its rich osteogenic potential. In this review, we describe the latest reports of preclinical and clinical studies on the bone-healing effects of Scl-Ab.
Citation Mihara A, Yukata K, Seki T, Iwanaga R, Nishida N, Fujii K, Nagao Y, Sakai T. Effects of sclerostin antibody on bone healing. World J Orthop 2021; 12(9): 651-659
Received
2021-03-08 09:33
Peer-Review Started
2021-03-08 09:36
To Make the First Decision
Return for Revision
2021-03-31 00:45
Revised
2021-04-12 12:49
Second Decision
2021-08-04 03:34
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief
2021-08-04 08:04
Articles in Press
2021-08-04 08:04
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript
2021-09-05 14:58
ISSN 2218-5836 (online)
Open Access This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/
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