Publication Name	World Journal of Transplantation
Manuscript ID	64744
Country	United States

Category	Gastroenterology & Hepatology
Manuscript Type	Retrospective Study
Article Title	Factors predicting futility of liver transplant in elderly recipients: A single-center experience
Manuscript Source	Invited Manuscript
All Author List	Cerise Kleb, Muhammad Salmam Faisal, Cristiano Quintini, Charles M Miller, K V Narayanan Menon and Jamak Modaresi Esfeh
Funding Agency and Grant Number
Corresponding Author	Jamak Modaresi Esfeh, MD, Assistant Professor, Department of Gastroenterology & Hepatology, Cleveland Clinic Foundation, 9500 Euclid Ave, Cleveland, OH 44195, United States. modarej@ccf.org
Key Words	Liver transplantation; Liver cirrhosis; Heart failure; Diastolic; Medical futility; Liver diseases; Organ transplantation
Core Tip	This was a retrospective study to identify factors associated with futility of liver transplant (LT) in elderly recipients, as well as investigate the risk of certain outcomes such as discharge to facility in elderly LT recipients. Diastolic congestive heart failure (CHF) was found to be a predictor of futility of LT in elderly recipients (P = 0.001). Elderly patients also had nearly twice the risk of being discharged to a facility and had decreased survival at one year. Diastolic CHF may be an important comorbidity for liver transplant committees to consider when deciding whether or not to list elderly patients.
Citation	Kleb C, Faisal MS, Quintini C, Miller CM, Menon KN, Modaresi Esfeh J. Factors predicting futility of liver transplant in elderly recipients: A single-center experience. World J Transplant 2021; 11(10): 421-431

Received	2021-02-23 02:38
Peer-Review Started	2021-02-23 02:42
To Make the First Decision
Return for Revision	2021-05-07 14:53
Revised	2021-05-19 23:10
Second Decision	2021-09-18 03:29
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief	2021-09-19 09:01
Articles in Press	2021-09-19 09:01
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript	2021-10-14 01:42

ISSN	2220-3230 (online)
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