Publication Name	World Journal of Gastrointestinal Oncology
Manuscript ID	64745
Country	Canada

Category	Gastroenterology & Hepatology
Manuscript Type	Review
Article Title	Proteasome regulators in pancreatic cancer
Manuscript Source	Invited Manuscript
All Author List	Nirosha J Murugan and Ioannis A Voutsadakis
Funding Agency and Grant Number
Corresponding Author	Ioannis A Voutsadakis, MD, PhD, Associate Professor, Doctor, Department of Medical Oncology, Sault Area Hospital, 750 Great Northern Road, Sault Sainte Marie P6A3T6, ON, Canada. ivoutsadakis@yahoo.com
Key Words	Pancreatic adenocarcinoma; Proteasome; Transcription factors; Regulation; Unfolded protein response; Cancer stem cells
Core Tip	Pancreatic adenocarcinoma is a gastrointestinal cancer with high incidence and bleak outcomes. The molecular pathways involved in the pathogenesis of the disease have been increasingly clarified in recent years. This article reviews the role of proteostasis regulation through the proteasome in pancreatic cancer. Major molecular pathways affected in pancreatic cancer closely interconnect with regulators of the proteasome.
Citation	Murugan NJ, Voutsadakis IA. Proteasome regulators in pancreatic cancer. World J Gastrointest Oncol 2022; 14(1): 38-54

Received	2021-02-23 02:12
Peer-Review Started	2021-02-23 02:16
To Make the First Decision
Return for Revision	2021-03-29 18:02
Revised	2021-04-14 13:34
Second Decision	2021-12-01 03:22
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief	2021-12-02 01:58
Articles in Press	2021-12-02 01:58
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript	2021-12-31 04:19

ISSN	1948-5204 (online)
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