Publication Name	World Journal of Clinical Oncology
Manuscript ID	64760
Country	Japan

Category	Oncology
Manuscript Type	Case Report
Article Title	Anaplastic myxopapillary ependymoma: A case report and review of literature
Manuscript Source	Invited Manuscript
All Author List	Hiroshi Kanno, Yukiko Kanetsuna and Masamichi Shinonaga
Funding Agency and Grant Number
Corresponding Author	Hiroshi Kanno, MD, PhD, Professor, Surgical Oncologist, Department of Neurosurgery, International University of Health and Welfare Atami Hospital, 13-1 East Coast, Atami 413-0012, Shizuoka, Japan. hiroshikannomd@nifty.com
Key Words	Myxopapillary ependymoma; Anaplastic feature; Pathological feature; Clinical feature; Management; Case report
Core Tip	Myxopapillary ependymoma (MPE) is a pathological grade I tumor that develops in the filum terminale. MPEs with anaplastic features are extremely rare; only 5 cases have shown malignancy when they relapsed. Here we report a case of MPE with anaplastic features in local late recurrence in a 46-year-old woman and review anaplastic MPE in the published literature. MPEs have the potential for malignant transformation after a long period of time despite being a pathological grade I tumor. Therefore, the possibility of malignant transformation of the MPE should be considered, and patients with MPE should be treated carefully and monitored over a long period of time.
Citation	Kanno H, Kanetsuna Y, Shinonaga M. Anaplastic myxopapillary ependymoma: A case report and review of literature. World J Clin Oncol 2021; 12(11): 1072-1082

Received	2021-02-23 08:53
Peer-Review Started	2021-02-23 08:58
To Make the First Decision
Return for Revision	2021-05-04 02:41
Revised	2021-05-17 23:56
Second Decision	2021-10-09 03:25
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief	2021-10-11 01:28
Articles in Press	2021-10-11 01:28
Publication Fee Transferred
Edit the Manuscript by Language Editor	2021-09-22 09:31
Typeset the Manuscript	2021-11-17 05:59

ISSN	2218-4333 (online)
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