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Publication Name World Journal of Hepatology
Manuscript ID 64838
Country Thailand
Category Transplantation
Manuscript Type Minireviews
Article Title Kidney transplant from donors with hepatitis B: A challenging treatment option
Manuscript Source Invited Manuscript
All Author List Praopilad Srisuwarn and Vasant Sumethkul
Funding Agency and Grant Number
Corresponding Author Vasant Sumethkul, FACP, FRCP (Hon), MD, Full Professor, Department of Medicine, Faculty of Medicine Ramathibodi Hospital, Mahidol University, 270 Rama 6 Road, Ratchathewi, Bangkok 10400, Thailand. vasant.sum@mahidol.ac.th
Key Words Hepatitis B virus; Organ donor; Recipient allocation; Kidney transplant; Transmission; Long term outcomes
Core Tip Low-risk hepatitis B surface antigen (HBsAg) positive kidney donor, defined by a negative test of hepatitis B virus (HBV) DNA being allocated to immune-recipients with anti-HBs at least 10 mIU/mL is a key factor in overcoming the risk of HBV transmission. The risk may be further eliminated with optimal nucleos(t)ide analog prophylaxis. Blood tests for HBV DNA, HBs Ag, and liver function tests should be routinely monitored after transplantation and when there is a change of immunosuppression. The excellent long-term outcomes being reported suggested that the outcomes of this treatment option are promising. This will lead to broader use of organs with positive HBsAg.
Citation Srisuwarn P, Sumethkul V. Kidney transplant from donors with hepatitis B: A challenging treatment option. World J Hepatol 2021; 13(8): 853-867
Received
2021-02-24 09:34
Peer-Review Started
2021-02-24 09:39
To Make the First Decision
Return for Revision
2021-06-04 05:04
Revised
2021-06-22 09:53
Second Decision
2021-07-29 02:54
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief
2021-07-29 06:01
Articles in Press
2021-07-29 06:01
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript
2021-08-18 08:18
ISSN 1948-5182 (online)
Open Access This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/
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