Publication Name	World Journal of Psychiatry
Manuscript ID	64849
Country	Spain

Category	Psychiatry
Manuscript Type	Minireviews
Article Title	Genetics of adult attachment: An updated review of the literature
Manuscript Source	Invited Manuscript
All Author List	Leire Erkoreka, Mercedes Zumarraga, Aurora Arrue, M Isabel Zamalloa, Ainara Arnaiz, Olga Olivas, Teresa Moreno-Calle, Estela Saez, Jon Garcia, Elena Marin, Noemi Varela, Ana Gonzalez-Pinto and Nieves Basterreche
Funding Agency and Grant Number
Corresponding Author	Leire Erkoreka, MD, PhD, Associate Chief Physician, Department of Psychiatry, Galdakao-Usansolo Hospital, Osakidetza Basque Health Service, Labeaga Auzoa 46A, Galdakao 48960, Spain. leire.erkorekagonzalez@osakidetza.eus
Key Words	Genetics; Adult attachment; Oxytocin; Dopamine; Serotonin; Brain-derived neurotrophic factor; Methylation
Core Tip	Attachment style influences adult cognitive, emotional and interpersonal functioning. Despite its relationship with early experiences, it is a malleable tendency that is shaped throughout the development. Genetic research indicates that up to 45% of the variability in anxious and 39% in avoidant adult attachment style could be explained by genetic causes. A narrative review is conducted analyzing the existing literature regarding the implication of candidate genes, with vulnerability and differential susceptibility approaches. We highlight the lack of genome-wide studies and scarcity of epigenetic investigation, concluding that further research is needed to clarify the etiological role of genetics on adult attachment.
Citation	Erkoreka L, Zumarraga M, Arrue A, Zamalloa MI, Arnaiz A, Olivas O, Moreno-Calle T, Saez E, Garcia J, Marin E, Varela N, Gonzalez-Pinto A, Basterreche N. Genetics of adult attachment: An updated review of the literature. World J Psychiatr 2021; 11(9): 530-542

Received	2021-02-25 09:50
Peer-Review Started	2021-02-25 09:53
To Make the First Decision
Return for Revision	2021-04-21 00:01
Revised	2021-05-04 07:14
Second Decision	2021-07-29 02:54
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief	2021-07-29 06:30
Articles in Press	2021-07-29 06:30
Publication Fee Transferred
Edit the Manuscript by Language Editor	2021-08-06 03:42
Typeset the Manuscript	2021-09-11 02:37

ISSN	2220-3206 (online)
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