Publication Name	World Journal of Gastrointestinal Surgery
Manuscript ID	65429
Country	Australia

Category	Oncology
Manuscript Type	Retrospective Study
Article Title	Oesophageal adenocarcinoma: In the era of extended lymphadenectomy, is the value of neoadjuvant therapy being attenuated?
Manuscript Source	Unsolicited Manuscript
All Author List	Jin-Soo Park, Hans Van der Wall, Catherine Kennedy and Gregory L Falk
Funding Agency and Grant Number
Corresponding Author	Jin-Soo Park, BMed, MD, MS, Doctor, Upper GI Surgery, Concord Repatriation General Hospital, Hospital Road, Concord, Sydney 2137, NSW, Australia. jinsoo.park@health.nsw.gov.au
Key Words	Oesophagectomy; Oesophageal adenocarcinoma; Neoadjuvant chemotherapy; Lymphadenectomy; Survival outcome; Surgical technique
Core Tip	This study aimed to compare the effect of neoadjuvant chemotherapy to a standardized surgery and lymphadenectomy on survival outcomes in curative oesophagectomy for cancer. Overall and disease-free survival were similar between neoadjuvant chemotherapy (NACT) and surgery only groups. There was improved survival in patients with ≥ 30 nodes harvested compared to those with < 30 nodes. The possibility that improved lymphadenectomy techniques, as opposed to NACT, improves survival outcomes in curative resection of oesophageal adenocarcinoma warrants further investigation.
Citation	Park JS, Van der Wall H, Kennedy C, Falk GL. Oesophageal adenocarcinoma: In the era of extended lymphadenectomy, is the value of neoadjuvant therapy being attenuated? World J Gastrointest Surg 2021; 13(10): 1235-1244

Received	2021-03-22 00:34
Peer-Review Started	2021-03-22 00:37
To Make the First Decision
Return for Revision	2021-08-15 19:06
Revised	2021-08-23 11:19
Second Decision	2021-09-17 03:30
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief	2021-09-19 09:10
Articles in Press	2021-09-19 09:10
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript	2021-10-15 00:29

ISSN	1948-9366 (online)
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