Publication Name	World Journal of Hepatology
Manuscript ID	65457
Country	United Arab Emirates

Category	Medicine, General & Internal
Manuscript Type	Opinion Review
Article Title	COVID-19 and the liver: What do we know so far?
Manuscript Source	Invited Manuscript
All Author List	Prashant Nasa and George Alexander
Funding Agency and Grant Number
Corresponding Author	Prashant Nasa, MD, Chief Doctor, Critical Care Medicine, NMC Specialty Hospital, Amman Street, Al Nahda 2, Dubai 7832, United Arab Emirates. dr.prashantnasa@hotmail.com
Key Words	COVID-19; Chronic liver disease; SARS-CoV-2; Severe acute respiratory syndrome coronavirus; Liver transplant; Liver and SARS-CoV-2 vaccines; SARS-CoV-2 induced liver injury
Core Tip	Liver involvement in coronavirus disease 2019 (COVID-19) is either due to viral cytotoxicity or secondarily to systemic immune dysregulation. Patients with pre-existing liver disease are at higher risk of disease progression, morbidity, and mortality. Chronic liver disease with COVID-19 should be managed as per the standard guidelines, with education on hand hygiene, social distance, and face masks to reduce hospital admissions. There is no evidence that currently available vaccines for severe acute respiratory syndrome will have any complications different from other inactivated vaccines and are recommended for patients with pre-existing liver disease, hepatocellular carcinoma, or liver transplant recipients.
Citation	Nasa P, Alexander G. COVID-19 and the liver: What do we know so far? World J Hepatol 2021; 13(5): 522-532

Received	2021-03-07 19:13
Peer-Review Started	2021-03-07 19:19
To Make the First Decision
Return for Revision	2021-03-29 14:51
Revised	2021-03-30 11:20
Second Decision	2021-04-29 09:21
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief	2021-04-29 11:35
Articles in Press	2021-04-29 11:35
Publication Fee Transferred
Edit the Manuscript by Language Editor	2021-05-06 20:06
Typeset the Manuscript	2021-05-19 01:18

ISSN	1948-5182 (online)
Open Access	This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/
Copyright	© The Author(s) 2021. Published by Baishideng Publishing Group Inc. All rights reserved.
Permissions	For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher	Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website	http://www.wjgnet.com