Publication Name	World Journal of Gastroenterology
Manuscript ID	65462
Country	China

Category	Gastroenterology & Hepatology
Manuscript Type	Basic Study
Article Title	Enhancer of zeste homolog 2 contributes to apoptosis by inactivating JAK2/STAT signaling in inflammatory bowel disease
Manuscript Source	Unsolicited Manuscript
All Author List	Jie Zhou, Yang Yang, Yi-Ling Wang, Yue Zhao, Wen-Jing Ye, Si-Yao Deng, Jin-Yi Lang and Shun Lu
Funding Agency and Grant Number	Funding Agency Grant Number National Natural Science Foundation of China 81900498
Corresponding Author	Shun Lu, MD, Chief Physician, Department of Radiation Oncology, Sichuan Cancer Hospital, No. 55 Renmin South Road, Chengdu 610041, Sichuan Province, China. lushousi90036@163.com
Key Words	Inflammatory bowel disease; Apoptosis; Enhancer of zeste homolog 2; JAK2; Permeability; Inflammatory bowel disease therapy
Core Tip	In this study, we discovered that enhancer of zeste homolog 2 (EZH2) contributed to apoptosis and inflammatory response by inactivating JAK2/STAT signaling in inflammatory bowel disease (IBD). EZH2 may be applied as the potential targets for IBD therapy.
Citation	Zhou J, Yang Y, Wang YL, Zhao Y, Ye WJ, Deng SY, Lang JY, Lu S. Enhancer of zeste homolog 2 contributes to apoptosis by inactivating JAK2/STAT signaling in inflammatory bowel disease. World J Gastroenterol 2021; 27(22): 3073-3084

Received	2021-03-07 17:57
Peer-Review Started	2021-03-07 18:01
To Make the First Decision
Return for Revision	2021-03-27 17:50
Revised	2021-04-09 07:41
Second Decision	2021-04-28 07:54
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief	2021-04-28 08:19
Articles in Press	2021-04-28 08:19
Publication Fee Transferred
Edit the Manuscript by Language Editor	2021-05-10 14:32
Typeset the Manuscript	2021-06-03 06:01

ISSN	1007-9327 (print) and 2219-2840 (online)
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