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4/28/2021 8:19:42 AM | Browse: 162 | Download: 179
Publication Name World Journal of Stem Cells
Manuscript ID 65586
Country United States
Category Biochemistry & Molecular Biology
Manuscript Type Review
Article Title Low complexity domains, condensates, and stem cell pluripotency
Manuscript Source Invited Manuscript
All Author List Munender Vodnala, Eun-Bee Choi and Yick W Fong
Funding Agency and Grant Number
Funding Agency Grant Number
National Institute of Health R01HL125527
Corresponding Author Yick W Fong, PhD, Assistant Professor, Department of Medicine, Cardiovascular Division, Brigham and Women's Hospital, Harvard Medical School, 75 Francis Street, Boston, Boston, MA 02115, United States. yfong@bwh.harvard.edu
Key Words Liquid-liquid phase separation; Embryonic stem cell; Pluripotency; Low complexity domain; Transcription; DNA damage response
Core Tip This review article discusses recent findings regarding the role of low-complexity domain proteins and phase separation in regulating key cellular processes in embryonic stem cells, including transcriptional activation and repression, cellular signaling integration, DNA damage response, and DNA repair.
Citation Vodnala M, Choi EB, Fong YW. Low complexity domains, condensates, and stem cell pluripotency. World J Stem Cells 2021; 13(5): 416-438
Received
2021-03-10 18:59
Peer-Review Started
2021-03-10 19:01
To Make the First Decision
Return for Revision
2021-04-19 18:17
Revised
2021-04-20 20:51
Second Decision
2021-04-28 07:51
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief
2021-04-28 08:19
Articles in Press
2021-04-28 08:19
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript
2021-05-25 05:51
ISSN 1948-0210 (online)
Open Access This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Copyright © The Author(s) 2021. Published by Baishideng Publishing Group Inc. All rights reserved.
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Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com