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9/10/2021 9:29:27 AM | Browse: 196 | Download: 206
Publication Name World Journal of Stem Cells
Manuscript ID 65758
Country/Territory Italy
Category Cell Biology
Manuscript Type Review
Article Title Unveiling the morphogenetic code: A new path at the intersection of physical energies and chemical signaling
Manuscript Source Invited Manuscript
All Author List Riccardo Tassinari, Claudia Cavallini, Elena Olivi, Valentina Taglioli, Chiara Zannini and Carlo Ventura
Funding Agency and Grant Number
Corresponding Author Carlo Ventura, MD, PhD, Director, Full Professor, National Laboratory of Molecular Biology and Stem Cell Engineering, National Institute of Biostructures and Biosystems – ELDOR LAB, Eldor Lab, at the Innovation Accelerator, CNR, Via Piero Gobetti 101, Bologna 40129, Italy. carlo.ventura@unibo.it
Key Words Physical energies; Stem cells; Bioelectricity; Electromagnetic radiation; Mechanical forces; Morphogenetic code
Core Tip The capability of biological systems to create dynamically evolving shapes, up to large-scale anatomy, raises a number of fundamental questions that are only partially addressed in terms of molecular signaling. Physical energies, including mechanical and electromagnetic waves, afford substantial control of somatic and stem cell fate under normal and pathological conditions. This editorial focuses on the remarkable role of bioelectricity in shape generation, and maintenance, up to growth regulatory patterning that lead to the specification of tissues/organs and of the whole individual. Implications of bioelectrical signaling in tissue regeneration and in the control of malignant transformation are also discussed.
Citation Tassinari R, Cavallini C, Olivi E, Taglioli V, Zannini C, Ventura C. Unveiling the morphogenetic code: A new path at the intersection of physical energies and chemical signaling. World J Stem Cells 2021; 13(10): 1382-1393
Received
2021-03-15 12:33
Peer-Review Started
2021-03-15 12:40
To Make the First Decision
Return for Revision
2021-05-06 18:12
Revised
2021-05-16 16:50
Second Decision
2021-09-09 03:22
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief
2021-09-10 09:29
Articles in Press
2021-09-10 09:29
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript
2021-10-19 08:33
ISSN 1948-0210 (online)
Open Access This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/
Copyright © The Author(s) 2021. Published by Baishideng Publishing Group Inc. All rights reserved.
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