Publication Name	World Journal of Gastrointestinal Oncology
Manuscript ID	65824
Country/Territory	Italy

Category	Gastroenterology and Hepatology
Manuscript Type	Review
Article Title	Moving forward in the treatment of cholangiocarcinoma
Manuscript Source	Invited Manuscript
All Author List	Tommaso M Manzia, Alessandro Parente, Ilaria Lenci, Bruno Sensi, Martina Milana, Carlo Gazia, Alessandro Signorello, Roberta Angelico, Giuseppe Grassi, Giuseppe Tisone and Leonardo Baiocchi
Funding Agency and Grant Number
Corresponding Author	Leonardo Baiocchi, MD, PhD, Associate Professor, Hepatology Unit, University of Tor Vergata, Viale Oxford 31, Rome 00133, Italy. baiocchi@uniroma2.it
Key Words	Cholangiocarcinoma; Treatment; Genetic aberration; Immunotherapy; Liver resection; Liver transplantation
Core Tip	Cholangiocarcinoma is a lethal malignancy characterized by a poor survival. In this review we discuss in detail the actual treatment and the future therapeutic perspectives for this cancer. Systemic and surgical strategies are reported with the corresponding results. Improved knowledge of this malignancy and a multidisciplinary therapeutic approach are likely to improve the cholangiocarcinoma outcome in the future.
Citation	Manzia TM, Parente A, Lenci I, Sensi B, Milana M, Gazia C, Signorello A, Angelico R, Grassi G, Tisone G, Baiocchi L. Moving forward in the treatment of cholangiocarcinoma. World J Gastrointest Oncol 2021; 13(12): 1939-1955

Received	2021-03-16 14:04
Peer-Review Started	2021-03-16 14:47
To Make the First Decision
Return for Revision	2021-05-03 05:04
Revised	2021-05-14 07:36
Second Decision	2021-10-12 08:02
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief	2021-10-14 03:09
Articles in Press	2021-10-14 03:09
Publication Fee Transferred
Edit the Manuscript by Language Editor	2021-09-24 21:49
Typeset the Manuscript	2021-12-07 04:36

ISSN	1948-5204 (online)
Open Access	This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/
Copyright	© The Author(s) 2021. Published by Baishideng Publishing Group Inc. All rights reserved.
Permissions	For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher	Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website	http://www.wjgnet.com

Assistant Editor	Assistant Editor
Science Editor	Kai-Le Chang (Online Science Editor)
Reviewer Code	06006609
Editorial Director
Journal Chief Editor
Company Chief Editor	Lian-Sheng Ma
Language Editor	Donna Fox
Production Editor	Ying-Yi Yuan
Responsible Production Editor	Ying-Yi Yuan
Responsible Science Editor
Proofing Editorial Director	Jin-Lei Wang
Proofing Editor-in-Chief	Lian-Sheng Ma

Full Article (PDF)	WJGO-13-1939.pdf
Full Article (Word)	WJGO-13-1939.docx
Manuscript File	65824_Auto_Edited-CKL-Filipodia.docx
Answering Reviewers	65824-Answering reviewers.pdf
Audio Core Tip	65824-Audio core tip.m4a
Conflict-of-Interest Disclosure Form	65824-Conflict-of-interest statement.pdf
Copyright License Agreement	65824-Copyright license agreement.pdf
Non-Native Speakers of English Editing Certificate	65824-Language certificate.pdf
Peer-review Report	65824-Peer-review(s).pdf
Scientific Misconduct Check	65824-Bing-Ma YJ-1.jpg
Scientific Misconduct Check	65824-Bing-Chang KL-2.jpg
Scientific Editor Work List	65824-Scientific editor work list.pdf