Publication Name	World Journal of Gastrointestinal Oncology
Manuscript ID	65824
Country	Italy

Category	Gastroenterology & Hepatology
Manuscript Type	Review
Article Title	Moving forward in the treatment of cholangiocarcinoma
Manuscript Source	Invited Manuscript
All Author List	Tommaso M Manzia, Alessandro Parente, Ilaria Lenci, Bruno Sensi, Martina Milana, Carlo Gazia, Alessandro Signorello, Roberta Angelico, Giuseppe Grassi, Giuseppe Tisone and Leonardo Baiocchi
Funding Agency and Grant Number
Corresponding Author	Leonardo Baiocchi, MD, PhD, Associate Professor, Hepatology Unit, University of Tor Vergata, Viale Oxford 31, Rome 00133, Italy. baiocchi@uniroma2.it
Key Words	Cholangiocarcinoma; Treatment; Genetic aberration; Immunotherapy; Liver resection; Liver transplantation
Core Tip	Cholangiocarcinoma is a lethal malignancy characterized by a poor survival. In this review we discuss in detail the actual treatment and the future therapeutic perspectives for this cancer. Systemic and surgical strategies are reported with the corresponding results. Improved knowledge of this malignancy and a multidisciplinary therapeutic approach are likely to improve the cholangiocarcinoma outcome in the future.
Citation	Manzia TM, Parente A, Lenci I, Sensi B, Milana M, Gazia C, Signorello A, Angelico R, Grassi G, Tisone G, Baiocchi L. Moving forward in the treatment of cholangiocarcinoma. World J Gastrointest Oncol 2021; 13(12): 1939-1955

Received	2021-03-16 14:04
Peer-Review Started	2021-03-16 14:47
To Make the First Decision
Return for Revision	2021-05-03 05:04
Revised	2021-05-14 07:36
Second Decision	2021-10-12 08:02
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief	2021-10-14 03:09
Articles in Press	2021-10-14 03:09
Publication Fee Transferred
Edit the Manuscript by Language Editor	2021-09-24 21:49
Typeset the Manuscript	2021-12-07 04:36

ISSN	1948-5204 (online)
Open Access	This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/
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