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Publication Name World Journal of Cardiology
Manuscript ID 66341
Country/Territory Greece
Category Cardiac and Cardiovascular Systems
Manuscript Type Review
Article Title Exercise-mediated adaptations in vascular function and structure: Beneficial effects in coronary artery disease
Manuscript Source Invited Manuscript
All Author List Xenofon M Sakellariou, Michail I Papafaklis, Eleni M Domouzoglou, Christos S Katsouras, Lampros K Michalis and Katerina K Naka
Funding Agency and Grant Number
Corresponding Author Michail I Papafaklis, FESC, MD, PhD, Attending Doctor, Consultant Physician-Scientist, Michailideion Cardiac Centre, University of Ioannina, Stavrou Niarchou Avenue, Ioannina 45100, Epirus, Greece. m.papafaklis@yahoo.com
Key Words Exercise; Endothelium; Flow-mediated dilation; Endothelial shear stress; Coronary artery disease; Hemodynamics
Core Tip Exercise has beneficial effects on the function and structure of the vasculature, thereby leading to a reduction of the cardiovascular risk. Hemodynamic forces, in particular endothelial shear stress, play a critical role in modulating the endothelial cell phenotype towards atherogenesis or atheroprotection. Exercise improves clinical outcomes in patients with coronary artery disease (CAD). We herein discuss the alterations induced by exercise on vascular function and structure, and the mechanisms involved in the benefits of exercise regarding patients with CAD.
Citation Sakellariou XM, Papafaklis MI, Domouzoglou EM, Katsouras CS, Michalis LK, Naka KK. Exercise-mediated adaptations in vascular function and structure: Beneficial effects in coronary artery disease. World J Cardiol 2021; In press
2021-03-25 19:42
Peer-Review Started
2021-03-25 19:46
To Make the First Decision
Return for Revision
2021-05-13 02:56
2021-05-30 15:34
Second Decision
2021-07-21 03:30
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief
2021-07-21 08:53
Articles in Press
2021-07-21 08:53
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript
ISSN 1949-8462 (online)
Open Access This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/
Copyright © The Author(s) 2021. Published by Baishideng Publishing Group Inc. All rights reserved.
Permissions For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Assistant Editor Assistant Editor
Science Editor Ya-Juan Ma
Reviewer Code 03413750
Editorial Director
Journal Chief Editor
Company Chief Editor Jia-Ping Yan
Language Editor
Production Editor
Responsible Production Editor
Responsible Science Editor
Proofing Editorial Director Jin-Lei Wang
Proofing Editor-in-Chief Lian-Sheng Ma
Manuscript File 66341_Auto_Edited-JPY.docx
Answering Reviewers 66341-Answering reviewers.pdf
Audio Core Tip 66341-Audio core tip.mp3
Conflict-of-Interest Disclosure Form 66341-Conflict-of-interest statement.pdf
Copyright License Agreement 66341-Copyright license agreement.pdf
Supplementary Material 66341-Copyright permission.pdf
Peer-review Report 66341-Peer-review(s).pdf
Scientific Misconduct Check 66341-Scientific misconduct check.pdf
Scientific Editor Work List 66341-Scientific editor work list.pdf