Publication Name	World Journal of Gastrointestinal Endoscopy
Manuscript ID	66731
Country	Japan

Category	Gastroenterology & Hepatology
Manuscript Type	Opinion Review
Article Title	Proposal of the term “gallstone cholangiopancreatitis” to specify gallstone pancreatitis that needs urgent endoscopic retrograde cholangiopancreatography
Manuscript Source	Unsolicited Manuscript
All Author List	Masatoshi Isogai
Funding Agency and Grant Number
Corresponding Author	Masatoshi Isogai, MD, Doctor, Surgeon, Department of Surgery, Nawa Hospital, 6-50, Fujie-cho, Ogaki 503-0852, Gifu, Japan. masatoshi.isogai@gmail.com
Key Words	Gallstone pancreatitis; Gallstone hepatitis; Acute cholangitis; Necrotizing pancreatitis; Pathophysiology; Endoscopic retrograde cholangiopancreatography
Core Tip	The term “gallstone cholangiopancreatitis (CP)” is suggested to specify gallstone acute pancreatitis complicated by life-threatening acute cholangitis due to persistent ampullary stone impaction and needs urgent endoscopic retrograde cholangiopancreatography with endoscopic sphincterotomy. The term “gallstone CP” incorporates the terms “cholangitis” and “gallstone pancreatitis.” “Cholangitis” refers to acute cholangitis due to cholangiovenous reflux through the foci of extensive hepatocyte necrosis reflexed by marked elevation in transaminase levels caused by persistent ampullary obstruction. “Gallstone pancreatitis” refers to elevated pancreatic enzyme levels consequent to pancreatic duct obstruction, the pancreatic lesion of which is characterized by minimal or mild inflammation.
Citation	Isogai M. Proposal of the term “gallstone cholangiopancreatitis” to specify gallstone pancreatitis that needs urgent endoscopic retrograde cholangiopancreatography. World J Gastrointest Endosc 2021; 13(10): 451-459

Received	2021-04-04 00:12
Peer-Review Started	2021-04-04 00:16
To Make the First Decision
Return for Revision	2021-06-25 12:42
Revised	2021-07-04 00:17
Second Decision	2021-07-29 02:54
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief	2021-07-29 07:10
Articles in Press	2021-07-29 07:10
Publication Fee Transferred
Edit the Manuscript by Language Editor	2021-08-17 22:14
Typeset the Manuscript	2021-10-12 02:56

ISSN	1948-5190 (online)
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