Publication Name	World Journal of Clinical Cases
Manuscript ID	67043
Country	China

Category	Immunology
Manuscript Type	Minireviews
Article Title	Regulatory roles of extracellular vesicles in immune responses against Mycobacterium tuberculosis infection
Manuscript Source	Invited Manuscript
All Author List	Zhi Yan, Hua Wang, Lan Mu, Zhi-De Hu and Wen-Qi Zheng
Funding Agency and Grant Number	Funding Agency Grant Number the Natural and Science Foundation of the Inner Mongolia Autonomous Region for Distinguished Young Scholars 2020JQ07 the Natural and Science Foundation of the Inner Mongolia Autonomous Region for General Programs 2020MS08126 the "Zhiyuan" Talent Project of the Inner Mongolia Medical University ZY0130013
Corresponding Author	Wen-Qi Zheng, MD, Research Scientist, Department of Laboratory Medicine, Affiliated Hospital of Inner Mongolia Medical University, No. 1 Tongdao North Street, Huimin District, Hohhot 010050, Inner Mongolia, China. zhengwenqi2011@163.com
Key Words	Extracellular vesicles; Exosomes; Mycobacterium tuberculosis; Infection; Antigen; Immune regulation
Core Tip	Extracellular vesicles (EVs) are nanoscale membrane-bound structures released by mammalian cells and bacteria and play essential regulatory roles in intercellular signal transduction and the immune response. In this review, the regulatory role of EVs released by Mycobacterium tuberculosis (Mtb)-infected cells in the anti-Mtb immune response was reviewed and discussed. Specifically, we focused on providing the most cutting-edge information on EVs released by Mtb-infected cells regulating the body’s immune response, including the regulatory roles in innate and acquired immune responses. In addition, the basis of EV-mediated regulation of the immune response is that the EVs released by Mtb-infected host cells contain Mtb-associated antigens, which is also described in detail.
Citation	Yan Z, Wang H, Mu L, Hu ZD, Zheng WQ. Regulatory roles of extracellular vesicles in immune responses against Mycobacterium tuberculosis infection. World J Clin Cases 2021; 9(25): 7311-7318

Received	2021-04-14 06:56
Peer-Review Started	2021-04-14 06:58
To Make the First Decision
Return for Revision	2021-05-11 17:33
Revised	2021-05-19 06:52
Second Decision	2021-08-04 03:32
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief	2021-08-04 07:24
Articles in Press	2021-08-04 07:24
Publication Fee Transferred
Edit the Manuscript by Language Editor	2021-08-09 13:28
Typeset the Manuscript	2021-08-24 00:16

ISSN	2307-8960 (online)
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