Publication Name	World Journal of Gastroenterology
Manuscript ID	67093
Country	Spain

Category	Gastroenterology & Hepatology
Manuscript Type	Frontier
Article Title	Recent insights into the characteristics and role of peritoneal macrophages from ascites of cirrhotic patients
Manuscript Source	Invited Manuscript
All Author List	Pilar García-Peñarrubia, Antonio José Ruiz-Alcaraz, Miriam Ruiz-Ballester, Tamara Nadira Ramírez-Pávez and María Martínez-Esparza
Funding Agency and Grant Number
Corresponding Author	Pilar García-Peñarrubia, MD, PhD, Full Professor, Senior Researcher, Department of Biochemistry and Molecular Biology B and Immunology, School of Medicine, University of Murcia, Campus de Espinardo, Murcia 30100, Spain. pigarcia@um.es
Key Words	Cirrhosis; Inflammation; Peritoneal macrophages; Phenotypic markers; Activation routes
Core Tip	This frontier article is based on a summary of recent relevant publications on the biology of mouse, as the main animal model used, and human peritoneal macrophages under the perspective of its future clinical translation to the role that these cells can play on several human liver diseases. Concretely, we have reviewed recent findings on several characteristics of human peritoneal macrophages obtained from the ascites of cirrhotic patients compared with those obtained from healthy donors. Featured article: Role of MAP kinases and PI3K-Akt on the cytokine inflammatory profile of peritoneal macrophages from the ascites of cirrhotic patients.
Citation	García-Peñarrubia P, Ruiz-Alcaraz AJ, Ruiz-Ballester M, Ramírez-Pávez TN, Martínez-Esparza M. Recent insights into the characteristics and role of peritoneal macrophages from ascites of cirrhotic patients. World J Gastroenterol 2021; 27(41): 7014-7024

Received	2021-04-14 17:47
Peer-Review Started	2021-04-14 17:50
To Make the First Decision
Return for Revision	2021-06-23 06:05
Revised	2021-07-02 12:07
Second Decision	2021-10-08 03:30
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief	2021-10-11 01:04
Articles in Press	2021-10-11 01:04
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript	2021-10-25 06:56

ISSN	1007-9327 (print) and 2219-2840 (online)
Open Access	This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/
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