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10/15/2021 8:59:56 AM | Browse: 130 | Download: 182
Publication Name World Journal of Stem Cells
Manuscript ID 67900
Country/Territory Italy
Category Physiology
Manuscript Type Basic Study
Article Title ARPE-19 conditioned medium promotes neural differentiation of adipose-derived mesenchymal stem cells
Manuscript Source Invited Manuscript
All Author List Giuliana Mannino, Martina Cristaldi, Giovanni Giurdanella, Rosario Emanuele Perrotta, Debora Lo Furno, Rosario Giuffrida and Dario Rusciano
Funding Agency and Grant Number
Funding Agency Grant Number
University of Catania, Italy, “Piano Triennale per la Ricerca 2020-2022–Grant PIACERI, project “NanoRet”
Corresponding Author Debora Lo Furno, PhD, Assistant Professor, Department of Biomedical and Biotechnological Sciences, University of Catania, Via Santa Sofia 97, Catania 95123, CT, Italy. lofurno@unict.it
Key Words Adipose-derived mesenchymal stem cells; Retinal pigment epithelium; Neural markers; Neural differentiation; Retina damage; Cell-based medicine
Core Tip Neural-like differentiation of adipose-derived stem cells (ASCs) was tested using a conditioned medium from ARPE-19 cells, a cell line derived from human retinal pigment epithelium. Following this treatment, the expression of typical glial and neuronal markers increased in a time-dependent manner. Neural-like differentiated ASCs may represent a valuable tool for cell-based therapeutic approaches in the field of regenerative medicine for the treatment of eye diseases.
Citation Mannino G, Cristaldi M, Giurdanella G, Perrotta RE, Lo Furno D, Giuffrida R, Rusciano D. ARPE-19 conditioned medium promotes neural differentiation of adipose-derived mesenchymal stem cells. World J Stem Cells 2021; 13(11): 1783-1796
2021-05-05 16:02
Peer-Review Started
2021-05-05 16:03
To Make the First Decision
Return for Revision
2021-06-23 14:50
2021-06-25 11:27
Second Decision
2021-10-15 06:33
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief
2021-10-15 08:59
Articles in Press
2021-10-15 08:59
Publication Fee Transferred
Edit the Manuscript by Language Editor
2021-09-29 03:52
Typeset the Manuscript
2021-11-22 05:02
ISSN 1948-0210 (online)
Open Access This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/
Copyright © The Author(s) 2021. Published by Baishideng Publishing Group Inc. All rights reserved.
Permissions For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Assistant Editor Assistant Editor
Science Editor Jia-Ru Fan
Reviewer Code 03726486, 06081653, and 03448879
Editorial Director
Journal Chief Editor
Company Chief Editor Lian-Sheng Ma
Language Editor Donna Fox
Production Editor Hua-Ge Yu
Responsible Production Editor Hua-Ge Yu
Responsible Science Editor
Proofing Editorial Director Jin-Lei Wang
Proofing Editor-in-Chief Lian-Sheng Ma
Full Article (PDF) WJSC-13-1783.pdf
Full Article (Word) WJSC-13-1783.docx
Manuscript File 67900_Auto_Edited-JRF-Filipodia.docx
Answering Reviewers 67900-Answering reviewers.pdf
Audio Core Tip 67900-Audio core tip.mp3
Biostatistics Review Certificate 67900-Biostatistics statement.pdf
Conflict-of-Interest Disclosure Form 67900-Conflict-of-interest statement.pdf
Copyright License Agreement 67900-Copyright license agreement.pdf
Approved Grant Application Form(s) or Funding Agency Copy of any Approval Document(s) 67900-Grant application form(s).pdf
Institutional Review Board Approval Form or Document 67900-Institutional review board statement.pdf
Non-Native Speakers of English Editing Certificate 67900-Language certificate.pdf
Peer-review Report 67900-Peer-review(s).pdf
Scientific Misconduct Check 67900-Bing-Fan JR-2.png
Scientific Editor Work List 67900-Scientific editor work list.pdf