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11/25/2021 2:41:03 AM | Browse: 23 | Download: 22
Publication Name World Journal of Stem Cells
Manuscript ID 68279
Country/Territory Serbia
Category Cell Biology
Manuscript Type Review
Article Title Dental mesenchymal stromal/stem cells in different microenvironments—implications in regenerative therapy
Manuscript Source Invited Manuscript
All Author List Ivana Okić-Đorđević, Hristina Obradović, Tamara Kukolj, Anđelija Petrović, Slavko Mojsilović, Diana Bugarski and Aleksandra Jauković
Funding Agency and Grant Number
Corresponding Author Ivana Okić-Đorđević, PhD, Assistant Professor, Laboratory for Experimental Hematology and Stem Cells, Institute for Medical Research, University of Belgrade, Dr Subotića 4, PO BOX 102, Belgrade 11129, Serbia. ivana.okic@imi.bg.ac.rs
Key Words Microenvironment; Dental mesenchymal stem cells; Modulation of regenerative potential; Tissue origin; Hypoxia microenvironment; Inflammatory microenvironment; Clinical application
Core Tip This review discusses recent advances in comparative analyses of dental mesenchymal stem cell (MSC) regeneration potential. We have summarized the available research evidence concerning the effects of hypoxic and inflammatory microenvironmental factors on dental MSC differentiation capacity. Existing investigations indicate the very important aspect of the recipient microenvironment niche in terms of therapeutic efficacy of transplanted dental MSCs. However, some of the data for the same cell type (especially in hypoxic in vitro conditions) are conflicting, so it is important to point out that the biology of MSCs is not yet fully known, and further research in this area is needed.
Citation Okić-Đorđević I, Obradović H, Kukolj T, Petrović A, Mojsilović S, Bugarski D, Jauković A. Dental mesenchymal stromal/stem cells in different microenvironments—implications in regenerative therapy. World J Stem Cells 2021; In press
Received
2021-05-17 13:38
Peer-Review Started
2021-05-17 13:43
To Make the First Decision
Return for Revision
2021-06-05 01:33
Revised
2021-06-15 13:18
Second Decision
2021-11-24 03:35
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief
2021-11-25 02:41
Articles in Press
2021-11-25 02:41
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript
ISSN 1948-0210 (online)
Open Access This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/
Copyright © The Author(s) 2021. Published by Baishideng Publishing Group Inc. All rights reserved.
Permissions For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Assistant Editor Assistant Editor
Science Editor Kai-Le Chang (Online Science Editor)
Reviewer Code 00504362, 03810998, 04738361, and 04738361
Editorial Director
Journal Chief Editor
Company Chief Editor Lian-Sheng Ma
Language Editor
Production Editor
Responsible Production Editor
Responsible Science Editor
Proofing Editorial Director Jin-Lei Wang
Proofing Editor-in-Chief Lian-Sheng Ma
Manuscript File 68279_Auto_Edited.docx
Answering Reviewers 68279-Answering reviewers.pdf
Audio Core Tip 68279-Audio core tip.mp3
Conflict-of-Interest Disclosure Form 68279-Conflict-of-interest statement.pdf
Copyright License Agreement 68279-Copyright license agreement.pdf
Approved Grant Application Form(s) or Funding Agency Copy of any Approval Document(s) 68279-Grant application form(s).pdf
Non-Native Speakers of English Editing Certificate 68279-Language certificate.pdf
Peer-review Report 68279-Peer-review(s).pdf
Scientific Misconduct Check 68279-Bing-Chang KL-2.jpg
Scientific Misconduct Check 68279-google-1.jpg
Scientific Editor Work List 68279-Scientific editor work list.pdf