Publication Name	World Journal of Gastrointestinal Oncology
Manuscript ID	70292
Country	China

Category	Gastroenterology & Hepatology
Manuscript Type	Clinical and Translational Research
Article Title	Association and prognostic significance of alpha-L-fucosidase-1 and matrix metalloproteinase 9 expression in esophageal squamous cell carcinoma
Manuscript Source	Unsolicited Manuscript
All Author List	Xiang-Yang Yu, Sheng-Cheng Lin, Meng-Qi Zhang, Xiao-Tong Guo, Kai Ma, Li-Xu Wang, Wen-Ting Huang, Zhe Wang, Xin Yu, Chun-Guang Wang, Lan-Jun Zhang and Zhen-Tao Yu
Funding Agency and Grant Number	Funding Agency Grant Number the Shenzhen Key Medical Discipline Construction Fund SZXK075 the Sanming Project of Medicine in Shenzhen SZSM201612097
Corresponding Author	Zhen-Tao Yu, MD, PhD, Surgical Oncologist, Department of Thoracic Surgery, National Cancer Center/National Clinical Research Center for Cancer/Cancer Hospital & Shenzhen Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, No. 113 Baohe Avenue, Longgang District, Shenzhen 518116, Guangdong Province, China. yztao2015@163.com
Key Words	Esophageal squamous cell carcinoma; Alpha-L-fucosidase-1; Matrix metalloproteinase-9; Immunohistochemistry
Core Tip	Our results demonstrated that high alpha-L-fucosidase-1 (FUCA1) expression was significantly associated with a worse overall survival, which illustrated that FUCA1 may have the ability to promote tumor cell invasion and metastasis among patients with esophageal squamous cell carcinoma (ESCC). Moreover, this study provides additional evidence that the molecular mechanisms of FUCA1 in ESCC are entirely different.
Citation	Yu XY, Lin SC, Zhang MQ, Guo XT, Ma K, Wang LX, Huang WT, Wang Z, Yu X, Wang CG, Zhang LJ, Yu ZT. Association and prognostic significance of alpha-L-fucosidase-1 and matrix metalloproteinase 9 expression in esophageal squamous cell carcinoma. World J Gastrointest Oncol 2022; 14(2): 498-510

Received	2021-08-12 09:18
Peer-Review Started	2021-08-12 09:22
To Make the First Decision
Return for Revision	2021-09-04 07:20
Revised	2021-09-06 03:25
Second Decision	2022-01-13 05:31
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief	2022-01-14 06:28
Articles in Press	2022-01-14 06:28
Publication Fee Transferred
Edit the Manuscript by Language Editor	2021-12-12 11:42
Typeset the Manuscript	2022-02-07 06:21

ISSN	1948-5204 (online)
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