Publication Name	World Journal of Clinical Cases
Manuscript ID	70605
Country	China

Category	Surgery
Manuscript Type	Case Report
Article Title	Diagnostic and surgical challenges of progressive neck and upper back painless masses in Madelung’s disease: A case report and review of literature
Manuscript Source	Unsolicited Manuscript
All Author List	Ya-Jie Yan, Shi-Qing Zhou, Chun-Qiao Li and Yan Ruan
Funding Agency and Grant Number	Funding Agency Grant Number National Natural Science Foundation of China (General Program) 81974581 Basic and Applied Research Foundation of Guangdong Province, China 2020A1515110407 Scientific Research Fund of Guangdong Provincial Bureau of Traditional Chinese Medicine China 20211200
Corresponding Author	Chun-Qiao Li, MD, Attending Doctor, Department of Otorhinolaryngology, the First Affiliated Hospital of Guangzhou University of Chinese Medicine, No. 16 Jichang Road, Baiyun District, Guangzhou 510405, Guangdong Province, China. lichunqiao18154920@163.com
Key Words	Madelung’s disease; Benign symmetric lipomatosis; Launois–Bensaude syndrome; Multiple symmetric lipomatosis; Lipectomy; Head and neck mass; Case report
Core Tip	Madelung’s disease (MD) is a rare chronic alcoholism-associated metabolic syndrome characterized by symmetrical deposition of adipose tissue subcutaneously in the head, neck, shoulders, back, trunk, and nerve roots of the upper and lower limbs. No consensus exists concerning the diagnosis, pathogenesis, and treatment of MD. Recently, a patient with MD accompanied by hypertension had undergone surgical resection and recovered well at our hospital. Herein, we present this case to improve clinicians’ diagnosis and treatment of MD while emphasizing the manifestations of MD presenting as head and neck masses.
Citation	Yan YJ, Zhou SQ, Li CQ, Ruan Y. Diagnostic and surgical challenges of progressive neck and upper back painless masses in Madelung’s disease: A case report and review of literature. World J Clin Cases 2022; 10(1): 361-370

Received	2021-08-19 11:36
Peer-Review Started	2021-08-19 11:38
To Make the First Decision
Return for Revision	2021-11-01 22:31
Revised	2021-11-14 04:17
Second Decision	2021-12-02 03:26
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief	2021-12-03 06:52
Articles in Press	2021-12-03 06:52
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript	2021-12-27 03:06

ISSN	2307-8960 (online)
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