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8/6/2022 8:27:04 PM | Browse: 82 | Download: 218
Publication Name World Journal of Clinical Cases
Manuscript ID 71501
Country/Territory China
Category Oncology
Manuscript Type Retrospective Study
Article Title Nomogram for predicting overall survival in Chinese triple-negative breast cancer patients after surgery
Manuscript Source Unsolicited Manuscript
All Author List Wei-Xun Lin, Yan-Na Xie, Yao-Kun Chen, Jie-Hui Cai, Juan Zou, Jie-Hua Zheng, Yi-Yuan Liu, Zhi-Yang Li and Ye-Xi Chen
Funding Agency and Grant Number
Funding Agency Grant Number
Special Fund Project of Guangdong Science and Technology 210728156901524, 210728156901519, 210714096870447
Medical Scientific Research Foundation of Guangdong Province A2021432, B2021448
Shantou Medical Science and Technology Planning Project 200622115260639, 210521236491457, 210625106490696
Undergraduate Innovation Training Project of Shantou University 31/38/47/54
Corresponding Author Ye-Xi Chen, MD, Doctor, Department of Thyroid, Breast and Hernia Surgery, The Second Affiliated Hospital of Shantou University Medical College, No. 69 North Dongxia Road, Shantou 515041, Guangdong Province, China. yxchen3@stu.edu.cn
Key Words Triple-negative breast cancer; Chinese; nomogram; Risk stratification; Overall survival
Core Tip This study aimed to construct and validate a nomogram for overall survival (OS) of triple-negative breast cancer (TNBC) patients after surgery. The data from SEER*stat 8.3.5 of selected Chinese surgical patients with TNBC between 2010 and 2015 were used. The multivariable analysis showed that age (P = 0.043), marital status (P = 0.040), tumor localization (P = 0.030), grade (P = 0.035), T classification (P = 0.012), and N classification (P = 0.002) were independent prognostic factors. A risk stratification model was generated. The C-indexes of the nomogram to predict OS were 0.766 and and compared to the seventh edition tumor, node and metastasis (TNM) staging system, which was higher (0.766 vs 0.707, P < 0.001). The nomogram provided a clear prognostic superiority over the traditional TNM system.
Citation Lin WX, Xie YN, Chen YK, Cai JH, Zou J, Zheng JH, Liu YY, Li ZY, Chen YX. Nomogram for predicting overall survival in Chinese triple-negative breast cancer patients after surgery. World J Clin Cases 2022; 10(31): 11338-11348
Received
2021-09-12 13:58
Peer-Review Started
2021-09-12 14:00
To Make the First Decision
Return for Revision
2022-01-10 08:54
Revised
2022-01-25 04:33
Second Decision
2022-08-03 02:40
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief
2022-08-06 20:27
Articles in Press
2022-08-06 20:27
Publication Fee Transferred
Edit the Manuscript by Language Editor
2022-09-28 17:26
Typeset the Manuscript
2022-10-13 06:59
ISSN 2307-8960 (online)
Open Access This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
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