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Publication Name World Journal of Neurology
Manuscript ID 74913
Country India
Category Neurosciences
Manuscript Type Minireviews
Article Title Role of cell-free DNA for predicting incidence and outcome of patients with ischemic stroke
Manuscript Source Unsolicited Manuscript
All Author List Nusrath Fathima, Sandhya Manorenj, Sandeep Kumar Vishwakarma and Aleem Ahmed Khan
Funding Agency and Grant Number
Corresponding Author Aleem Ahmed Khan, PhD, N/A, N/A, Central Laboratory for Stem Cell Research and Translational Medicine, Centre for Liver Research and Diagnostics, Deccan College of Medical Sciences, DMRL X Road, Hyderabad 500058, Telangana, India. aleem_a_khan@rediffmail.com
Key Words Ischemic stroke; Mitochondria; Circulating cell-free DNA; Plasma nucleic acid; Mortality
Core Tip Early and accurate diagnosis of ischemic stroke is critical to achieve favorable clinical outcome. Cell-free DNA can be used as a useful biomarker for early diagnosis and prognosis of ischemic stroke for saving time and increasing the likelihood of successful intervention. Discriminative quantification of cell free mitochondrial DNA instead of overall circulating DNA may provide more significant value for identifying real-time host response. The future practical adoption of this strategy may be aided by reliable and standardized quantification of cell-free mitochondrial DNAs in ischemic stroke patients to design more effective diagnosis, prognosis and therapeutic strategies.
Citation Fathima N, Manorenj S, Vishwakarma SK, Khan AA. Role of cell-free DNA for predicting incidence and outcome of patients with ischemic stroke. World J Neurol 2022; 8(1): 1-9
Received
2022-01-11 07:23
Peer-Review Started
2022-01-11 07:24
To Make the First Decision
Return for Revision
2022-05-31 02:35
Revised
2022-06-11 02:04
Second Decision
2022-07-25 07:59
Accepted by Journal Editor-in-Chief
Accepted by Executive Editor-in-Chief
2022-07-31 20:48
Articles in Press
2022-07-31 20:48
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript
2022-08-29 01:03
ISSN 2218-6212 (online)
Open Access This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
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