Publication Name	World Journal of Gastroenterology
Manuscript ID	75024
Country	Japan

Category	Gastroenterology & Hepatology
Manuscript Type	Minireviews
Article Title	Assessment of physical stress during the perioperative period of endoscopic submucosal dissection
Manuscript Source	Invited Manuscript
All Author List	Daisuke Chinda and Tadashi Shimoyama
Funding Agency and Grant Number	Funding Agency Grant Number The Karoji Memorial Fund for Medical Research
Corresponding Author	Tadashi Shimoyama, FACG, MD, PhD, Director, Department of Internal Medicine, Aomori General Health Examination Center, 2-12-19 Tsukuda, Aomori 030-0962, Japan. tsimo@hirosaki-u.ac.jp
Key Words	Physical stress; Endoscopic submucosal dissection; Indirect calorimeter; Resting energy expenditure; Chemiluminescence; Serum opsonic activity
Core Tip	Concerning the degree of physical invasiveness of patients before and after endoscopic submucosal dissection (ESD), assessment methods based on changes in energy metabolism using an indirect calorimeter and serum opsonic activity (SOA) measured by lucigenin- and luminol-dependent chemiluminescence are useful and easy to measure. During the perioperative period of ESD, the increase in resting energy expenditure and stress factor were lower than those reported for surgery, and SOA changes involved a minor increase in the production of lower-toxicity reactive oxygen species. These assessment methods demonstrated that the physical stress of ESD is less invasive than that of surgery.
Citation	Chinda D, Shimoyama T. Assessment of physical stress during the perioperative period of endoscopic submucosal dissection. World J Gastroenterol 2022; 28(32): 4508-4515

Received	2022-01-14 06:44
Peer-Review Started	2022-01-14 06:45
To Make the First Decision
Return for Revision	2022-04-16 06:06
Revised	2022-04-28 07:02
Second Decision	2022-07-29 02:52
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief	2022-08-01 03:54
Articles in Press	2022-08-01 03:54
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript	2022-08-03 06:23

ISSN	1007-9327 (print) and 2219-2840 (online)
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