BPG is committed to discovery and dissemination of knowledge
Articles in Press
6/20/2022 3:46:45 PM | Browse: 62 | Download: 19
Publication Name World Journal of Gastroenterology
Manuscript ID 75137
Country/Territory United States
Category Gastroenterology and Hepatology
Manuscript Type Review
Article Title Tumor microenvironment in pancreatic ductal adenocarcinoma: Implications in immunotherapy
Manuscript Source Invited Manuscript
All Author List Caitlyn Smith, Wei Zheng, Jixin Dong, Yaohong Wang, Jinping Lai, Xiuli Liu and Feng Yin
Funding Agency and Grant Number
Corresponding Author Feng Yin, MD, PhD, Assistant Professor, Department of Pathology and Anatomical Sciences, University of Missouri, One Hospital Drive, MSB M263, Columbia, MO 65212, United States. fengyin@health.missouri.edu
Key Words Pancreatic ductal adenocarcinoma; Tumor microenvironment; Immunotherapy; Clinical trial; Chemotherapy; Treatment
Core Tip Despite advances in basic and translational research, pancreatic cancer remains one of the most lethal cancers. Recent breakthroughs in immunotherapy have revolutionized cancer therapy and have shown great potential to transform pancreatic cancer treatment. However, due to the barrier related to the tumor microenvironment, pancreatic cancer has shown inferior treatment outcomes toward various immunotherapy regimens. Further efforts, such as combinatory immunotherapy or molecular tumor subtyping, are warranted to overcome immunotherapy resistance in pancreatic cancer.
Citation Smith C, Zheng W, Dong J, Wang Y, Lai J, Liu X, Yin F. Tumor microenvironment in pancreatic ductal adenocarcinoma: Implications in immunotherapy. World J Gastroenterol 2022; In press
Received
2022-01-16 20:49
Peer-Review Started
2022-01-16 20:50
To Make the First Decision
Return for Revision
2022-04-11 08:47
Revised
2022-04-22 15:21
Second Decision
2022-06-13 03:14
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief
2022-06-20 15:46
Articles in Press
2022-06-20 15:46
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript
2022-06-23 09:09
ISSN 1007-9327 (print) and 2219-2840 (online)
Open Access This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Copyright © The Author(s) 2022. Published by Baishideng Publishing Group Inc. All rights reserved.
Permissions For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Assistant Editor Assistant Editor
Science Editor Ya-Juan Ma.
Reviewer Code 05123031, 05260764, 03261315, 05260764, and 03261315
Editorial Director
Journal Chief Editor
Company Chief Editor Li Ma
Language Editor
Production Editor Wen-Wen Qi
Responsible Production Editor
Responsible Science Editor
Proofing Editorial Director Jin-Lei Wang
Proofing Editor-in-Chief Lian-Sheng Ma
Manuscript File 75137_Auto_Edited_LM.docx
Answering Reviewers 75137-Answering reviewers.pdf
Audio Core Tip 75137-Audio core tip.m4a
Conflict-of-Interest Disclosure Form 75137-Conflict-of-interest statement.pdf
Copyright License Agreement 75137-Copyright license agreement.pdf
Non-Native Speakers of English Editing Certificate 75137-Language certificate.pdf
Peer-review Report 75137-Peer-review(s).pdf
Scientific Editor Work List 75137-Scientific editor work list.pdf