BPG is committed to discovery and dissemination of knowledge
Articles in Press
5/8/2022 7:17:50 AM | Browse: 134 | Download: 207
Publication Name World Journal of Stem Cells
Manuscript ID 75421
Country/Territory India
Category Immunology
Manuscript Type Basic Study
Article Title Soluble factors secreted by human Wharton’s jelly mesenchymal stromal/stem cells exhibit therapeutic radioprotection-a mechanistic study with integrating network biology
Manuscript Source Invited Manuscript
All Author List Dharmendra Kumar Maurya, Mayuri Bandekar and Santosh Kumar Sandur
Funding Agency and Grant Number
Corresponding Author Dharmendra Kumar Maurya, BSc, MSc, PhD, N/A, Radiation Biology and Health Sciences Division, Bhabha Atomic Research Centre, 3-82-S, A-block, Modular Laboratory, Mumbai 400085, Maharashtra, India. dkmaurya@barc.gov.in
Key Words Radioprotection; Mesenchymal stem cells; Wharton's jelly-derived mesenchymal stromal/stem cells; Cytokines; Granulocyte-colony stimulating factor; Network biology
Core Tip This study showed the potential role of cytokine granulocyte-colony stimulating factor in therapeutic radioprotection. Transcriptome analysis shows that Wharton's jelly-derived mesenchymal stromal/stem cells (WJ-MSCs) have unique set of genes compared to bone marrow MSCs and embryonic stem cells. WJ-MSCs secrete several cytokines which promote cellular pathways which handle tissue repair and regeneration.
Citation Maurya DK, Bandekar M, Sandur SK. Soluble factors secreted by human Wharton’s jelly mesenchymal stromal/stem cells exhibit therapeutic radioprotection: A mechanistic study with integrating network biology. World J Stem Cells 2022; 14(5): 347-361
Received
2022-01-28 07:44
Peer-Review Started
2022-01-28 07:46
To Make the First Decision
Return for Revision
2022-03-11 23:43
Revised
2022-03-25 05:32
Second Decision
2022-05-07 07:56
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief
2022-05-08 07:17
Articles in Press
2022-05-08 07:17
Publication Fee Transferred
Edit the Manuscript by Language Editor
2022-04-28 20:53
Typeset the Manuscript
2022-05-23 07:36
ISSN 1948-0210 (online)
Open Access This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Copyright © The Author(s) 2022. Published by Baishideng Publishing Group Inc. All rights reserved.
Permissions For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com