Publication Name	World Journal of Clinical Cases
Manuscript ID	75602
Country	Mexico

Category	Medicine, Research & Experimental
Manuscript Type	Letter to the Editor
Article Title	Stem cells as an option for the treatment of COVID-19
Manuscript Source	Invited Manuscript
All Author List	Maria Veronica Cuevas-González and Juan Carlos Cuevas-González
Funding Agency and Grant Number
Corresponding Author	Juan Carlos Cuevas-González, PhD, Academic Research, Institute of Biomedical Sciences, Autonomous University of Ciudad Juárez, Av. Benjamín Franklin No. 4650, Zona Pronaf Condominio La Plata, Ciudad Juarez 32310, Chihuahua, Mexico. cuevas_gonzalez@hotmail.com
Key Words	COVID-19; Stem cells; Multiple diseases; Undifferentiated cells; Appropriate treatment; Cytokines granulocyte-macrophage colony-stimulating factor
Core Tip	The stem-cell-derived microvesicles improve the oxygenation conditions of patients, thereby avoiding mechanical oxygenation methods. They demonstrate the ability to modulate the inflammatory response by reducing the levels of proinflammatory cytokines within the first few hours of their intravenous application, because these microvesicles contain cytokines, growth factors, and microRNAs, which function as anti-inflammatory agents.
Citation	Cuevas-González MV, Cuevas-González JC. Stem cells as an option for the treatment of COVID-19. World J Clin Cases 2022; 10(18): 6338-6340

Received	2022-02-06 21:40
Peer-Review Started	2022-02-06 21:42
To Make the First Decision
Return for Revision	2022-03-23 09:01
Revised	2022-04-01 00:20
Second Decision	2022-05-11 03:02
Accepted by Journal Editor-in-Chief
Accepted by Executive Editor-in-Chief	2022-05-12 20:15
Articles in Press	2022-05-12 20:15
Publication Fee Transferred
Edit the Manuscript by Language Editor	2022-05-09 21:24
Typeset the Manuscript	2022-06-01 13:42

ISSN	2307-8960 (online)
Open Access	This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Copyright	©The Author(s) 2022. Published by Baishideng Publishing Group Inc. All rights reserved.
Permissions	For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher	Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website	http://www.wjgnet.com