Publication Name	World Journal of Gastroenterology
Manuscript ID	75878
Country	China

Category	Radiology, Nuclear Medicine & Medical Imaging
Manuscript Type	Prospective Study
Article Title	Differential diagnosis of different types of solid focal liver lesions using two-dimensional shear wave elastography
Manuscript Source	Unsolicited Manuscript
All Author List	Jia Guo, Dong Jiang, Yi Qian, Jiao Yu, Yi-Jun Gu, Yu-Qing Zhou and Hui-Ping Zhang
Funding Agency and Grant Number	Funding Agency Grant Number Natural Science Foundation of Shanghai of China 19ZR1441500 Natural Science Foundation of Shanghai of China 22ZR1458200 Science Research Foundation of Shanghai Municipal Health Commission 202140378 Key Program of Science and Technology Commission Foundation of Changning, Shanghai, China CNKW2020Z04
Corresponding Author	Hui-Ping Zhang, Doctor, MD, PhD, Associate Chief Physician, Department of Ultrasound, Shanghai Changning Maternity and Infant Health Hospital, East China Normal University, No. 786 Yuyuan Road, Shanghai 200050, China. zhanggirldan@163.com
Key Words	Focal liver lesions; Conventional ultrasound; Two-dimensional shear wave elastography; Differential diagnosis
Core Tip	Two-dimensional shear wave elastography (2D-SWE) could address the limitations of point SWE and provide overall elastic information in tumors and locate the stiffest part of the tumors. We used 2D-SWE with maximal elasticity to measure the stiffness of focal liver lesions (FLLs) and to explore the value of 2D-SWE in the differential diagnosis of FLLs, especially among different pathological types of malignant FLLs. Our results showed malignant FLLs were stiffer than benign ones and liver metastases were stiffer than primary liver carcinomas. 2D-SWE with Emax was useful complement to conventional ultrasound for the differential diagnosis of FLLs.
Citation	Guo J, Jiang D, Qian Y, Yu J, Gu YJ, Zhou YQ, Zhang HP. Differential diagnosis of different types of solid focal liver lesions using two-dimensional shear wave elastography. World J Gastroenterol 2022; 28(32): 4716-4725

Received	2022-04-06 09:53
Peer-Review Started	2022-04-06 09:53
To Make the First Decision
Return for Revision	2022-06-27 23:32
Revised	2022-07-15 06:25
Second Decision	2022-07-29 02:52
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief	2022-08-01 03:52
Articles in Press	2022-08-01 03:52
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript	2022-08-03 05:47

ISSN	1007-9327 (print) and 2219-2840 (online)
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